推薦產品
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
10.1, monoclonal
形狀
buffered aqueous solution
物種活性
human, nonhuman primates
濃度
1 mg/mL
技術
flow cytometry: suitable
同型
IgG1
NCBI登錄號
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... FCGR1(2209)
相關類別
一般說明
The mouse monoclonal antibody 10.1 recognizes alpha subunit of CD64/FcgammaRI, a 72 kDa single chain type I glycoprotein, that is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes.
免疫原
Rheumatoid synovial fluid cells and fibronectin purified human monocytes
應用
Cluster of differentiation 64 (CD64) has been implicated in various immunological processes such as phagocytosis, the clearance of immune complexes and the secretion of immunological mediators. In addition, it also facilitates antibody-dependent cellular cytotoxicity, the modulation of B-cell differentiation and transcytosis of IgG across the epithelial layer. Neutrophil CD64 serves as a potent diagnostic marker for bacterial infection and neonatal sepsis.
生化／生理作用
The cluster of differentiation 64 (CD64), also known as Fc fragment of IgG receptor Ia (FCGR1A), gene is mapped to human chromosome lq21.2--q21.3. The gene codes for a 72 kDa glycoprotein that is constitutively expressed on human monocytes and macrophages.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Neutrophil CD64 as a diagnostic marker for neonatal sepsis: Meta-analysis.
Dai J, et al.
Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University, 327-332 (2017)
Yunqin Lee et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 22(14), 3571-3581 (2016-02-13)
Human tumors consist of heterogeneous populations of cells with distinct marker expression and functional properties. In squamous cell carcinoma of the head and neck (SCCHN), CD44 is a well-characterized marker of a resilient subpopulation of cells associated with increased tumorigenesis
Neutrophil CD64 expression as a longitudinal biomarker for severe disease and acute infection in critically ill patients.
Jong E, et al.
International Journal of Laboratory Hematology, 38(5), 576-584 (2016)
Human high-affinity Fc?RI (CD64) gene mapped to chromosome 1q21.2-q21.3 by fluorescence in situ hybridization
Takai S, et al.
Human Genetics, 93(1), 13-15 (1994)
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