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Merck
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重要文件

SAB4502671

Sigma-Aldrich

Anti-RPL39, N-Terminal antibody produced in rabbit

affinity isolated antibody

同義詞:

60S ribosomal protein L39

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
暫時無法取得訂價和供貨情況

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 6 kDa

物種活性

human, rat, mouse

濃度

~1 mg/mL

技術

ELISA: 1:60000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... RPL39(6170)

相關類別

一般說明

Ribosomal protein L39 (RPL39), a component of the 60S ribosomal complex. The RPL39 gene is mapped on human chromosome XQ24.

免疫原

The antiserum was produced against synthesized peptide derived from human RPL39.

Immunogen Range: 1-50

生化/生理作用

Ribosomal protein L39 (RPL39) plays a major role in spermatogenesis and translation. It might participate in ribosome biogenesis. Mutations in the RPL39 gene are associated with breast cancer and lung metastasis. RPL39 is capable of disrupting nitric oxide synthase and hypoxia signaling pathway. Overexpression of RPL39 can enhance wound-healing in MDAMB231 and BT549 cells. Antibody detects endogenous levels of total RPL39 protein.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Bhuvanesh Dave et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(24), 8838-8843 (2014-05-31)
We previously described a gene signature for breast cancer stem cells (BCSCs) derived from patient biopsies. Selective shRNA knockdown identified ribosomal protein L39 (RPL39) and myeloid leukemia factor 2 (MLF2) as the top candidates that affect BCSC self-renewal. Knockdown of

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