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Merck
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重要文件

SAB4502128

Sigma-Aldrich

Anti-PDE4D antibody produced in rabbit

affinity isolated antibody

同義詞:

DPDE3, PDE43, PDE4D4, cAMP-specific 3′,5′-cyclic phosphodiesterase 4D

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
共軛:
unconjugated
application:
ELISA
IHC
WB
無性繁殖:
polyclonal
物種活性:
human, mouse, rat
citations:
4
技術:
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
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生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 91 kDa

物種活性

human, mouse, rat

濃度

~1 mg/mL

技術

ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... PDE4D(5144)

一般說明

Anti-PDE4D Antibody detects endogenous levels of total PDE4D protein.

免疫原

The antiserum was produced against synthesized peptide derived from human PDE4D.

Immunogen Range: 156-205

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Dibyadeep Datta et al.
Cerebral cortex (New York, N.Y. : 1991), 33(24), 11501-11516 (2023-10-24)
Alzheimer's disease cortical tau pathology initiates in the layer II cell clusters of entorhinal cortex, but it is not known why these specific neurons are so vulnerable. Aging macaques exhibit the same qualitative pattern of tau pathology as humans, including
Dibyadeep Datta et al.
Frontiers in neuroanatomy, 14, 578483-578483 (2020-12-18)
cAMP signaling has powerful, negative effects on cognitive functions of the primate dorsolateral prefrontal cortex (dlPFC), opening potassium channels to reduce firing and impair working memory, and increasing tau phosphorylation in aging neurons. This contrasts with cAMP actions in classic
Fikru B Bedada et al.
Scientific reports, 6, 36803-36803 (2016-11-12)
Molecular inotropy refers to cardiac contractility that can be modified to affect overall heart pump performance. Here we show evidence of a new molecular pathway for positive inotropy by a cardiac-restricted microRNA (miR). We report enhanced cardiac myocyte performance by
Shannon N Leslie et al.
Frontiers in aging neuroscience, 12, 576723-576723 (2020-11-17)
Age is the largest risk factor for Alzheimer's disease (AD) and contributes to cognitive impairment in otherwise healthy individuals. Thus, it is critical that we better understand the risk aging presents to vulnerable regions of the brain and carefully design

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