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Merck

1.04166

SAFC

尿素

granulated, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS

製藥生產

同義詞:

碳酰二胺, 碳酰胺

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About This Item

線性公式:
NH2CONH2
CAS號碼:
分子量::
60.06
Beilstein:
635724
MDL號碼:
分類程式碼代碼:
12352111

等級

ACS reagent

品質等級

agency

BP
ChP
JP
Ph. Eur.
USP

產品線

EMPROVE® EXPERT

形狀

granular

pH值

9

mp

132-135 °C (lit.)

密度

1.335 g/mL at 25 °C (lit.)

應用

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

運輸包裝

ambient

SMILES 字串

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI 密鑰

XSQUKJJJFZCRTK-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing processes and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, granulated urea is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Urea is typically used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. It is useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. Urea may be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
Due to its low microbial and endotoxin limits, Urea granulated Emprove® Expert is especially suitable for high-risk applications.
用于蛋白质变性以及作为不溶性或变性蛋白的温和增溶剂。可用于从已由 6M 盐酸胍变性的样品(如包涵体)复性蛋白质。可与盐酸胍和二硫苏糖醇 (DTT) 一起用于复性变性蛋白以恢复其天然或活性形式。

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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應用

產品號碼
描述
訂價

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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文章

Handling bulk powders at a large scale in the pharmaceutical, biopharmaceutical, and bioprocessing setting is challenging. Compared to powders, granulated materials experience far less caking, have better flowability, and are easier to handle, even after long-term storage.

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