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重要文件

SAB4502012

Sigma-Aldrich

抗-INOS 兔抗

affinity isolated antibody

同義詞:

NOS2A, 一氧化氮合成酶, 巨噬细胞, 诱导型

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
暫時無法取得訂價和供貨情況

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 131 kDa

物種活性

human

濃度

~1 mg/mL

技術

ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... NOS2(4843)

一般說明

INOS(诱导型一氧化氮合酶)基因定位于人类染色体17q11.2。
抗-INOS抗体可检测内源性总INOS蛋白水平。

免疫原

该抗血清是针对衍生自人iNOS的合成肽而生成的。

免疫原范围: 1101-1150

應用

兔抗INOS,C端抗体可用于免疫印迹。

生化/生理作用

在感染、组织损伤和炎症期间观察到INOS(诱导型一氧化氮合酶)的上调。INOS负责产生NO(一氧化氮),通过诱导血管舒张来控制血流。NO充当神经递质,可以促进免疫反应。NO还可以响应氧化应激、缺氧、炎性细胞因子(TNF-α,IL-1β,IFN-γ)和脂多糖内毒素而产生抗血栓形成和抗炎作用。iNOS比神经元和内皮NOS产生更多的NO。与这两种同工型不同,iNOS与钙无关。INOS可能与2型糖尿病有关。

特點和優勢

完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多信息。

外觀

兔IgG,溶于磷酸盐缓冲液(不含Mg2+和Ca2+),pH 7.4,150mM NaCl,0.02%叠氮化钠和50%甘油中。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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