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SAB4301578

Sigma-Aldrich

抗 磷酸化 ERK1/2 (pThr 202/Tyr204 ) 兔抗

affinity isolated antibody

同義詞:

ERK-1, ERK1, ERT2, P44ERK1, PRKM3

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

42 kDa
44 kDa

物種活性

rat, mouse, human

濃度

1.0 mg/mL

技術

western blot: 1:500-1:1000 (Cell Lysate)

同型

IgG

登錄號

NP_001035145.1 

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pThr202/pTyr204)

基因資訊

human ... MAPK3(5595)

特異性

抗体只有在苏氨酸 202 和酪氨酸 204磷酸化时检测内源性 p44/42 MAP 激酶水平。

免疫原

来源于人 p44/42 MAP 激酶的苏氨酸 202/酪氨酸 204 (F-L-T (p)-E-Y (p)-V-A) 磷酸化位点附近的肽序列。

特點和優勢

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外觀

溶于1.0mg/mL磷酸盐缓冲盐水(不含Mg2+和Ca2+),pH 7.4,含150mM NaCl、0.02%叠氮化钠和50%甘油。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Vittorio Perfetti et al.
Oncotarget, 8(34), 56158-56167 (2017-09-17)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5' end of the receptor juxtamembrane
Varun Kumar et al.
Current eye research, 46(5), 710-718 (2020-10-28)
Understanding molecular changes is essential for designing effective treatments for nonarteritic anterior ischemic optic neuropathy (AION), the most common acute optic neuropathy in adults older than 50 years. We investigated changes in the mitogen-activated protein kinase (MAPK) pathway after experimental AION
Lenka Halova et al.
Open biology, 11(4), 200405-200405 (2021-04-08)
Fluctuations in TOR, AMPK and MAP-kinase signalling maintain cellular homeostasis and coordinate growth and division with environmental context. We have applied quantitative, SILAC mass spectrometry to map TOR and nutrient-controlled signalling in the fission yeast Schizosaccharomyces pombe. Phosphorylation levels at
Ravinder K Goyal et al.
BMC genomics, 19(1), 178-178 (2018-03-07)
The mitogen-activated protein kinase (MAPK) family is involved in signal transduction networks that underpin many different biological processes in plants, ranging from development to biotic and abiotic stress responses. To date this class of enzymes has received little attention in
M Paauwe et al.
Oncogene, 35(31), 4069-4079 (2016-01-26)
Endoglin, a transforming growth factor-β co-receptor, is highly expressed on angiogenic endothelial cells in solid tumors. Therefore, targeting endoglin is currently being explored in clinical trials for anti-angiogenic therapy. In this project, the redundancy between endoglin and vascular endothelial growth

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