推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
50kDa
物種活性
rabbit, human, horse, bovine, pig, dog
濃度
0.5 mg - 1 mg/mL
技術
immunoblotting: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... TUBB6(84617)
一般說明
Tubulin, β 6 class V (TUBB6) is encoded by a multigene family.It is located on human chromosome 18p11.21.
免疫原
Synthetic peptide directed towards the N terminal region of human TUBB6
生化／生理作用
Tubulin, β 6 class V (TUBB6) expression expression is correlated with microtubule stability. TUBB6 expression decreases in most tumors. Mutation in TUBB6 leads to velopharyngeal dysfunction, bilateral ptosis and congenital non-progressive facial palsy.Increased production of TUBB6 causes complete disruption of microtubule network and lowers pyroptosis.
序列
Synthetic peptide located within the following region: QLERINVYYNESSSQKYVPRAALVDLEPGTMDSVRSGPFGQLFRPDNFIF
外觀
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death
Salinas,, et al.
Molecular Biology of the Cell, 25(1), 76-86 (2014)
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
Dempster,, et al.
Human Molecular Genetics, 20(24), 4786-4796 (2011)
A TUBB6 mutation is associated with autosomal dominant non-progressive congenital facial palsy, bilateral ptosis and velopharyngeal dysfunction
Fazeli, W, et al.
Human Molecular Genetics, 26(20), 4055-4066 (2017)
Tumoral and tissue-specific expression of the major human beta-tubulin isotypes.
Leandro-Garcia LJ
Cytoskeleton (Hoboken, N.J.), 67(4), 214-223 (2010)
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