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重要文件

S9875

Sigma-Aldrich

胆酸钠

同義詞:

Choleic Acid Sodium Salt, Desoxycholic acid sodium salt

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About This Item

分類程式碼代碼:
12161900
NACRES:
NA.25
暫時無法取得訂價和供貨情況

應用

胆酸钠已用于评估食管腺癌对胆汁盐抗性的研究。 [1] 它还用于研究假定的酪氨酸-O-硫酸盐受体在酪氨酸硫化蛋白的靶向和/或细胞内转运中的作用。 [2]

其他說明

这是一个宽泛使用的术语,适用于粗牛胆汁提取物,其中含有牛磺胆酸、甘氨胆酸、脱氧胆酸和胆酸的钠盐。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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The Resistance of Esophageal Adenocarcinoma to Bile Salt Insult is Associated with Manganese Superoxide Dismutase Expression
Schiffman, S., et al.
The Journal of Surgical Research, 171, 8-8 (2011)
M C Liu et al.
Cytotechnology, 23(1-3), 143-149 (1997-01-01)
By employing the affinity gel fraction technique, we have detected a 175 kDa tyrosine-O-sulfate (TyrS)-binding protein in sodium choleate extracts of the microsomal membrane fractions of bovine liver and pancreas, as well as canine liver and pancreas. Western blot analysis
Suguru Yamasaki et al.
Scientific reports, 9(1), 177-177 (2019-01-19)
During infection, Salmonella senses and responds to harsh environments within the host. Persistence in a bile-rich environment is important for Salmonella to infect the small intestine or gallbladder and the multidrug efflux system AcrAB-TolC is required for bile resistance. The
Giovanni Sorrentino et al.
Gastroenterology, 159(3), 956-968 (2020-06-03)
Renewal and patterning of the intestinal epithelium is coordinated by intestinal stem cells (ISCs); dietary and metabolic factors provide signals to the niche that control ISC activity. Bile acids (BAs), metabolites in the gut, signal nutrient availability by activating the

Questions

  1. I would like to know that is this product suitable for neonatal mouse experiment?

    1 answer
    1. This product has not been tested in neonatal mouse studies. The researcher would have to establish suitability. There is a cell culture tested product option, C9282, that may be a better option. The product is not sterile, but has been tested for cytotoxicity in mammalian cell lines. See below for a link to this product.
      https://www.sigmaaldrich.com/product/sigma/c9282

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