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D6898

Sigma-Aldrich

脱氧核糖核酸 钠盐 来源于鲱鱼睾丸

Type XIV

同義詞:

DNA

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
41106305
eCl@ss:
32160414
NACRES:
NA.51

一般說明

来自鲱鱼睾丸的脱氧核糖核酸钠盐,也称为HtDNA,是DNA结合剂研究的天然DNA来源。 HtDNA的检出限约为5.0ng,光散射强度(I(LS))的线性范围为0.05 ~ 2.5 mµg。

應用

从鲱鱼睾丸中提取的脱氧核糖核酸钠盐被用于研究调节DNA结构和功能的DNA结合剂。鲱鱼睾丸DNA也用于溶液中DNA行为的物理化学研究。

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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X Du et al.
Talanta, 55(1), 93-98 (2008-10-31)
The interaction of histone with nucleic acids was characterized by light-scattering measurement using a common spectrofluorometer. Thereby, a sensitive and convenient method for the determination of nucleic acids was established. At pH 4.5-6.5, the interaction of histone with nucleic acids
Assaf Marcus et al.
Immunity, 49(4), 754-763 (2018-10-18)
Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second messenger that binds and activates the adaptor protein STING, which leads to interferon (IFN) production. Here, we found that in vivo natural killer (NK) cell killing
Larisa I Labzin et al.
The EMBO journal, 38(21), e101365-e101365 (2019-08-31)
Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro-inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to
Gillian Dunphy et al.
Molecular cell, 71(5), 745-760 (2018-09-08)
DNA damage can be sensed as a danger-associated molecular pattern by the innate immune system. Here we find that keratinocytes and other human cells mount an innate immune response within hours of etoposide-induced DNA damage, which involves the DNA sensing
Renée M Van der Sluis et al.
PLoS pathogens, 16(2), e1008151-e1008151 (2020-02-29)
HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4+ T cells. Latently infected CD4+ T cells do not

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