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Merck
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重要文件

S3523

Sigma-Aldrich

表面肌动蛋白

from Bacillus subtilis, ≥98.0% (HPLC)

同義詞:

surfactin C

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About This Item

經驗公式(希爾表示法):
C53H93N7O13
CAS號碼:
分子量::
1036.34
分類程式碼代碼:
51102829
PubChem物質ID:
NACRES:
NA.85
暫時無法取得訂價和供貨情況

生物源

Bacillus subtilis

品質等級

描述

zwitterionic

化驗

≥98.0% (HPLC)

形狀

powder

儲存條件

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

顏色

white to faint yellow

CMC

7.5-20 μmol/L (depending on methods)

溶解度

ethanol: soluble 10 mg/mL

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria
fungi
mycoplasma
neoplastics
viruses

作用方式

cell membrane | interferes

儲存溫度

2-8°C

SMILES 字串

CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1

InChI

1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1

InChI 密鑰

NJGWOFRZMQRKHT-WGVNQGGSSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

化学结构:肽

應用

表面活性素可用作表面活性剂用于介导单价和二价阳离子,如钙在脂质双层膜上的流通。 它还可用于研究抗肿瘤活性、抗包膜病毒活性、抗巨大芽孢杆菌原生质体活性以及抗支原体活性[1]

生化/生理作用

表面活性素是一种脂肽抗生素,由具有长脂肪酸部分的一个β-羟基脂肪酸和七个氨基酸组成。 其中三个具有D构象。 它是一种强大的生物表面活性剂,可引起红细胞和细菌的溶解。 它也是一种凝血抑制剂。 表面活性素被认为是通过与膜发生物理化学相互作用而对膜进行破坏或解体[1]

其他說明

保存于密闭容器内,置于干燥通风处。置于干燥处保存。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

M M Nakano et al.
Journal of bacteriology, 170(12), 5662-5668 (1988-12-01)
Surfactin is a lipopeptide antibiotic produced by the cells of Bacillus subtilis ATCC 21332. A genetic locus responsible for surfactin production (sfp) was transferred from ATCC 21332 to JH642, a derivative of the standard B. subtilis 168. To study the
Darlane Wellen Freitas de Oliveira et al.
Colloids and surfaces. B, Biointerfaces, 101, 34-43 (2012-07-17)
In this work a low cost medium for the production of a biosurfactant by Bacillus subtilis LAMI005 and the kinetics of surfactin production considering the effect of initial substrate concentration were investigated. First, cashew apple juice supplementation for optimal production
Guillaume Henry et al.
Cellular microbiology, 13(11), 1824-1837 (2011-08-16)
The lipopeptide surfactin secreted by plant-beneficial bacilli has crucial biological functions among which the ability to stimulate immune-related responses in host tissues. This phenomenon is important for biological control of plant diseases but its molecular basis is still poorly understood.
N Behary et al.
Colloids and surfaces. B, Biointerfaces, 90, 137-143 (2011-11-08)
This article deals with an alternative method for bio-separation of surfactin produced by Bacillus subtilis using sorption method on nonwoven PET (polyethylene terephthalate) fibrous membranes functionalized with chitosan. In the first part of the study, surface functionalization of the PET
Junfeng Zhao et al.
Journal of industrial microbiology & biotechnology, 39(6), 889-896 (2012-02-22)
Genome shuffling is an efficient approach for the rapid improvement of the yield of secondary metabolites. This study was undertaken to enhance the yield of surfactin produced by Bacillus amyloliquefaciens ES-2-4 using genome shuffling and to examine changes in SrfA

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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