As reported in the 'DESCRIPTION' section of the product page, Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. This product has not been further characterized.
推薦產品
一般說明
硫苷脂(Sulfatide)是一种糖鞘脂,在宿主-病原体识别、β-细胞功能、感染、止血/血栓形成、蛋白运输、细胞生长、细胞黏附、神经可塑性、细胞形态发生与信号转导中起重要作用。[1][2]存在于各种血细胞表面,包括血小板、白细胞和红细胞。硫苷脂也存在于血清中,作为脂蛋白的糖鞘脂。[3]它由聚糖部分、疏水部分、3-O-硫酸半乳糖和神经酰胺组成,其中神经酰胺由鞘氨醇碱基和脂肪酸组成。[1]它是维持髓鞘和轴-胶连接正确形成的重要组分。硫苷脂的生产变异与癌症和免疫病等各种人类疾病有关。硫苷脂的代谢变化会导致突触功能障碍、神经功能减退、炎症和髓鞘恶化。[1]
硫苷脂是主要由半乳脑神经苷硫酸盐组成的 3-O-磺基半乳糖基神经酰胺。它位于髓鞘中,约占脑中总髓磷脂的 4%。[4]
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
從最近期的版本中選擇一個:
分析證明 (COA)
Lot/Batch Number
客戶也查看了
C Mazurier et al.
Bailliere's clinical haematology, 9(2), 229-241 (1996-06-01)
von Willebrand disease (vWD), the most common congenital bleeding disorder in man, is related to quantitative and/or qualitative abnormalities of von Willebrand factor (vWF), a protein necessary for platelet-vessel wall interactions and for carrying factor VIII. Distinct abnormalities of vWF
Mamoru Kyogashima
Archives of biochemistry and biophysics, 426(2), 157-162 (2004-05-26)
In 1961, Wago et al. reported a potential anticoagulant role for sulfatide using animal experiments. Since then there have been many studies of sulfatide in the field of thrombogenesis/haemostasis, yielding contradictory conclusions. Some report that sulfatide has anti-thrombotic activity because
A recombinant two-module form of human properdin is an inhibitor of the complement alternative pathway
Kouser L, et al.
Molecular Immunology, 73(11), 76-87 (2016)
Age-and brain region-specific effects of dietary vitamin K on myelin sulfatides
Crivello NA, et al.
The Journal of Nutritional Biochemistry, 21(11), 1083-1088 (2010)
Quantification of sulfatides and lysosulfatides in tissues and body fluids by liquid chromatography tandem mass spectrometry
Mirzaian M, et al.
Journal of Lipid Research, 56(8), 936-943 (2015)
文章
Discover Bioactive Small Molecules for Lipid Signaling Research
-
Hi, Do you have any information about the sulfatide composition/profile of “Sulfatide from bovine brain (S1006)”.
1 answer-
Helpful?
-
Active Filters
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務