推薦產品
物種活性
mouse
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.1 ng/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
mouse ... Esm1(71690)
一般說明
This ELISA antibody pair detects mouse Endothelial Cell-specific Molecule 1. Endothelial cell-specific molecule 1 (ESM1) is a secreted dermatan sulfate proteoglycan. This cysteine-rich protein is expressed in kidney glomeruli, specifically in renal epithelia and endothelial cells. Proangiogenic factors and cytokines modulate its activity.
應用
请参考Protocol了解详情。
生化/生理作用
Endothelial cell-specific molecule 1 (ESM1) may have a role in inflammation and angiogenesis. It has been linked to tumor growth. ESM1 stimulates vascular sprouting, growth, differentiation, migration and adhesion of cells.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1).
Biochemical and Biophysical Research Communications (2006)
ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma.
Oncotarget (2016)
The non glycanated endocan polypeptide slows tumor growth by inducing stromal inflammatory reaction.
Oncotarget (2015)
Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.
Circulation Research (2014)
Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy.
PLoS ONE (2017)
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