推薦產品
化驗
≥98% (HPLC)
形狀
solid
溶解度
DMSO: 16 mg/mL
起源
Roche
儲存溫度
2-8°C
SMILES 字串
CCC1(O)CC2N(CCc3cc(OC)c(OC)cc23)CC1CC(C)C
InChI
1S/C21H33NO3/c1-6-21(23)12-18-17-11-20(25-5)19(24-4)10-15(17)7-8-22(18)13-16(21)9-14(2)3/h10-11,14,16,18,23H,6-9,12-13H2,1-5H3
InChI 密鑰
TUNMGCULOKMBNJ-UHFFFAOYSA-N
生化／生理作用
Ro 4-1284 is a reversible VMAT2 inhibitor.
特點和優勢
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
M E Maragoudakis et al.
Microvascular research, 50(2), 215-222 (1995-09-01)
A method providing a biochemical index for the evaluation of promoters or inhibitors of angiogenesis in the chick chorioallantoic membrane (CAM) is here described and validated. This method is based on the determination of collagenous protein synthesis which takes place
M Q Paiva et al.
Naunyn-Schmiedeberg's archives of pharmacology, 348(5), 466-471 (1993-11-01)
The aim of the present work was to study the influence of tissue morphological characteristics on the neuronal release (and by inference the distribution) of tritiated and endogenous noradrenaline. Rat vas deferens and dog spleen capsule were loaded with 0.2
S Yehuda et al.
European journal of pharmacology, 365(1), 27-34 (1999-02-13)
Ro4-1284 (2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a] quinolizin-2-ol hydrochloride), a benzoquinolizine, is a potent dopamine depletion agent whose acute and chronic administration results in a (1) deterioration of learning in the Morris Water Maze and passive avoidance tasks, (2) decrease in locomotion and rearing, (3)
M E Maragoudakis et al.
Kidney international, 43(1), 147-150 (1993-01-01)
Basement membrane (BM) exerts profound influence on endothelial cell (EC) behavior. In addition BM is a structural element of blood vessels; in fact at some point of their formation blood vessels are bare EC tubes lined with the BM produced
J E Leysen et al.
European journal of pharmacology, 206(1), 39-45 (1991-01-25)
[3H]Ketanserin was found to label (besides a low amount of 5-HT2 receptors) non-serotonergic binding sites on human platelet membranes. The latter binding was detected in the presence of excess of the 5-HT2 antagonist BW501, and was potently inhibited by tetrabenazine.
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