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重要文件

P3513

Sigma-Aldrich

多聚-L-赖氨酸,琥珀酰化

mol wt >50,000

同義詞:

改性赖氨酸共聚物

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About This Item

MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.26
暫時無法取得訂價和供貨情況

形狀

powder or solid

分子量

>50,000

顏色

white to faint yellow

應用

cell analysis

儲存溫度

−20°C

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應用

琥珀酰化聚-L-赖氨酸已用于结合 (Gly)3-Arg-缓激肽,用于研究脑内肽酶和胰蛋白酶对其的水解。[1]

生化/生理作用

聚-L-赖氨酸是一种阳离子聚合物。它主要用于将细胞固定在玻璃基板或带负电的基板上。[2][3]
蛋白质与聚-L-赖氨酸偶联的中间体。

分析報告

分子量基于前体聚-L-赖氨酸的粘度。还通过MALLS被检测。

其他說明

如需有关聚氨基酸的更多技术信息,请访问聚氨基酸常见问题解答资源

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Sofia Helena Linnea Frost et al.
Cancer biotherapy & radiopharmaceuticals, 26(6), 727-736 (2011-11-18)
Avidin-coupled monoclonal antibody MX35 (avidin-MX35) and astatine-211-labeled, biotinylated, succinylated poly-l-lysine ((211)At-B-PL(suc)) were administered in mice to assess potential efficacy as an intraperitoneal (i.p.) therapy for microscopic tumors. We aimed to establish a timeline for pretargeted radioimmunotherapy using these substances, and
Effects of poly(L-lysine) substrates on attached Escherichia coli bacteria.
Colville K
Langmuir, 26(4), 2639-2644 (2010)
Susceptibility of a Peptide Derived from Bradykinin to Hydrolysis by Brain Endo-oligopeptidases and Pancreatic Proteinases*
Antonio C. M. Camargo
The Journal of Biological Chemistry, 254(12), 5304-5307 (1979)
M R Hamblin et al.
British journal of cancer, 89(5), 937-943 (2003-08-28)
Conjugates between photosensitisers (PS) and charged polymeric carriers are under investigation for photodynamic therapy of cancer and may allow targeting to certain cell types or compartments in tumours. Covalent attachment of polyethylene glycol to macromolecules (pegylation) may alter their pharmacokinetics
V S Trubetskoy et al.
Nucleic acids research, 27(15), 3090-3095 (1999-08-24)
DNA can be condensed with an excess of poly-cations in aqueous solutions forming stable particles of submicron size with positive surface charge. This charge surplus can be used to deposit alternating layers of polyanions and polycations on the surface surrounding

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