跳轉至內容
Merck
全部照片(3)

重要文件

P1750

Sigma-Aldrich

胰脂肪酶 来源于猪胰腺

4 × USP specifications

同義詞:

胰液素 来源于猪胰腺

登入查看組織和合約定價


About This Item

CAS號碼:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54
暫時無法取得訂價和供貨情況

agency

USP (specifications)

形狀

powder

比活性

4 × USP specifications

包含

lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)

儲存溫度

−20°C

尋找類似的產品? 前往 產品比較指南

相關類別

應用

来自猪胰腺的胰酶已被用于:
  • 评估脂肪酶补充疗法治疗脂肪泻的研究[1]
  • 研究慢性胰腺炎失代偿期患者的胰腺糖尿病治疗方案[2]
  • 安全有效地从动脉移植物中去除福尔马林固定的组织,而不造成结构损伤和纤维完整性的损失 [3]
  • 评估消化酶的切割效果。
  • 用于 体外消化率分析和纤维素分解细菌抑制剂敏感性的测试。[4]
  • 与淀粉葡萄糖苷酶一起用于食品样品中的淀粉体外消化。[5]

生化/生理作用

胰酶由猪胰腺的外分泌细胞产生,含有胰蛋白酶、淀粉酶和脂肪酶、核糖核酸酶和蛋白酶等酶组份。 这种酶的组合使其能够水解蛋白质、淀粉和脂肪。 在 40°C 水中,胰酶在 5 分钟内将不少于其重量 25 倍的马铃薯淀粉转化为可溶性碳水化合物,在 pH7.5,40℃ 下,胰酶在 60 分钟内消化不少于重量 25 倍的酪蛋白,在 pH9.0,37℃ 下,每毫克胰酶每分钟将从橄榄油中释放不低于微当量的酸。

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

David C Whitcomb et al.
Digestive diseases and sciences, 52(1), 1-17 (2007-01-06)
A primary function of the pancreas is to produce digestive enzymes that are delivered to the small intestine for the hydrolysis of complex nutrients. Much of our understanding of digestive enzymes comes from studies in animals. New technologies and the
Muhammad Awais et al.
Foods (Basel, Switzerland), 9(5) (2020-05-28)
The changes in structure and digestion properties of mung bean starch due to hydrothermal treatment at various controlled temperatures were investigated. Results showed the increase in onset temperature (To) from 66.33 °C to 76.69 °C and decrease in enthalpies (∆Hg
Gabriele Rocchetti et al.
Antioxidants (Basel, Switzerland), 9(4) (2020-04-10)
In this work, different commercial extra-virgin olive oils (EVOO) were subjected to in vitro gastrointestinal digestion and the changes in bioactive compounds were evaluated by ultra-high-pressure liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry, using untargeted metabolomics. As expected, raw EVOO
Peter Layer et al.
Pancreas, 26(1), 1-7 (2002-12-25)
Treatment of steatorrhea by lipase supplementation therapy has become more successful in the last decade due to better understanding of the physiology and pathophysiology of the digestive process. Porcine lipase has been the therapeutic standard for several decades and will
T Nakamura et al.
Pancreas, 16(3), 329-336 (1998-04-21)
Pancreatic steatorrhea and pancreatic diabetes are the dominant symptoms of patients in the decompensated stage of chronic pancreatitis (CP). In this stage, the nutritional state is greatly disturbed and hypoglycemia and labile infection are involved. Pancreatic enzyme replacement therapy is

Questions

1–4 of 4 Questions  
  1. units of pancreatin cas number 8049-47-6

    1 answer
    1. This product meets 4X the minimum USP specifications. According to the USP monograph for Pancreatin, the 1X minimum specification is 25 USP units amylase, 2 USP units lipase, and 25 USP units protease per milligram. The calculated protease activity for the 4X preparation then, would be at least 100 units per milligram. This is a calculated value based on the USP monograph and are not reported separately on the Certificate of Analysis.

      Helpful?

  2. What is the trypsin activity of this P1750 product ?

    1 answer
    1. This product is not specifically tested for trypsin activity. The material meets USP requirements. This monograph includes testing for protease, amylase, and lipase.

      Helpful?

  3. What is the solubility of p1750 pancreatin in water?

    1 answer
    1. This product is soluble at 7 mg/mL in water and may yield a hazy solution.

      Helpful?

  4. As per USP: Pancreatin contains, in each mg, not less than 25 USP Units of protease activity. I assume that product P1750 contains minimum 100 USP units of protease activity in each mg. What is the maximum USP units of protease activity in P1750 ?

    1 answer
    1. Yes, this is correct. To meet the USP specifications, the protease activity will be less than 100 USP Units/mg.

      Helpful?

Reviews

No rating value

Active Filters

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務