P0080

普伦司特 半水合物

≥98% (HPLC), white, solid

• 同義詞: 8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran
• 經驗公式（希爾表示法）: C₂₇H₂₃N₅O₄ · 0.5 H₂O
• CAS號碼: 150821-03-7
• 分子量：: 490.51
• MDL號碼: MFCD24539454
• 分類程式碼代碼: 51111800
• PubChem物質ID: 329820009
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 顏色: white
• 溶解度: DMSO: ≥10 mg/mL; H₂O: insoluble
• 儲存溫度: −20°C
• SMILES 字串: O.O=C(Nc1cccc2C(=O)C=C(Oc12)c3nnn[nH]3)c4ccc(OCCCCc5ccccc5)cc4.O=C(Nc6cccc7C(=O)C=C(Oc67)c8nnn[nH]8)c9ccc(OCCCCc%10ccccc%10)cc9
• InChI: 1S/2C27H23N5O4.H2O/c2*33-23-17-24(26-29-31-32-30-26)36-25-21(23)10-6-11-22(25)28-27(34)19-12-14-20(15-13-19)35-16-5-4-9-18-7-2-1-3-8-18;/h2*1-3,6-8,10-15,17H,4-5,9,16H2,(H,28,34)(H,29,30,31,32);1H2
• InChI 密鑰: MSXTUBJFNBZPGC-UHFFFAOYSA-N

描述

生化／生理作用

Pranlukast is a subtype specific CysLT1 receptor antagonist. Leukotrienes are involved in the inflammation response and are divided into two main classes; leukotriene B4 and cysteinyl-substituted leukotrienes.

特點和優勢

This compound is featured on the Leukotriene Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H315,H319,H335,H413
• 防範說明: P273 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves