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MAK123

Sigma-Aldrich

α-葡萄糖苷酶活性检测试剂盒

sufficient for 100 colorimetric tests

同義詞:

α-Glucosidase Test Kit

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.84

用途

sufficient for 100 colorimetric tests

檢測方法

colorimetric

相關疾病

endocrinological disorders, diabetes; neurological disorders

儲存溫度

−20°C

基因資訊

human ... GAA(2548)
mouse ... GAA(14387)
rat ... GAA(367562)

一般說明

α-葡萄糖苷酶作用于末端非还原a(1→4)-连接D-葡萄糖残基,水解糖水化合物,释放D-葡萄糖。庞佩氏症和糖尿病会出现葡萄糖苷酶异常。

應用

α葡萄糖苷酶活性分析是结合被用来检测a-葡萄糖苷酶活性。

特點和優勢

兼容高通量的操作系统。

適合性

适用于测定生物样品中的α-葡萄糖苷酶活性。

原則

在本检测中,α-葡糖苷酶活性通过α-葡糖苷酶水解 对硝基苯基-α-D吡喃葡萄糖苷的反应确定,该反应形成比色(405 nm)产物,与存在的α-葡糖苷酶活性成比例。

儲存類別代碼

10 - Combustible liquids


分析證明 (COA)

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Epigallocatechin gallate affects glucose metabolism and increases fitness and lifespan in Drosophila melanogaster.
Wagner A E, et al.
Oncotarget, 6(31), 30568-30568 (2015)
Youngse Oh et al.
Molecules (Basel, Switzerland), 26(2) (2021-01-16)
Catalpa pod has been used in traditional medicine for the treatment of diabetes mellitus in South America. Studies on the constituents of Catalpa species have shown that it is rich in iridoids. In the present study, three previously undescribed compounds
Structure of human lysosomal acid a-glucosidase?a guide for the treatment of Pompe disease.
Veronique R Z, et al.
Nature Communications, 8(1), 1111-1111 (2017)
Anika E Wagner et al.
Oncotarget, 6(31), 30568-30578 (2015-09-17)
In this study, we tested whether a standardized epigallocatechin-3-gallate (EGCG) rich green tea extract (comprising > 90% EGCG) affects fitness and lifespan as well as parameters of glucose metabolism and energy homeostasis in the fruit fly, Drosophila melanogaster. Following the
Inhibitory effect of rhubarb on intestinal a-glucosidase activity in type 1 diabetic rats.
Hou K J, et al.
Tropical Journal of Pharmaceutical Research, 16(6), 1293-1297 (2017)

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