推薦產品
用途
sufficient for 100 colorimetric tests
檢測方法
colorimetric
相關疾病
hematological disorder
儲存溫度
−20°C
一般說明
葡萄糖6-磷酸 (G6P) 是进入代谢途径或储存的关键代谢中间体。葡萄糖被己糖激酶或葡糖激酶磷酸化时，或在糖原分解过程中被磷酸葡糖变位酶转化为葡萄糖-1-磷酸时，产生 G6P。G6P 位于糖酵解和戊糖磷酸途径的起点。当血糖水平高时，它也可以储存为糖原。[1]
適合性
适用于定量各种样品中的葡萄糖-6-磷酸。
原則
G6P 被葡萄糖-6-磷酸脱氢酶利用，以 NADPH 的形式产生还原当量。这对红细胞特别重要，因为 G6PDH 缺乏可导致溶血性贫血。通过酶测定法测定 G6P，其产生与存在的 G6P 成比例的比色 (450 nm) 产物。 典型的检测灵敏度在 1-30 纳摩尔之间。
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
從最近期的版本中選擇一個：
分析證明 (COA)
Lot/Batch Number
MiR-182 promotes glucose metabolism by upregulating hypoxia-inducible factor 1a in NSCLC cells
Mingliang W, et al.
Biochemical and Biophysical Research Communications, 504(2), 400-405 (2018)
Renal Disease in Type I Glycogen Storage Disease
Richard P L, et al.
Genetic Diseases of the Kidney (2009)
Saixiang Feng et al.
Veterinary research, 51(1), 97-97 (2020-08-02)
Lipooligosaccharides (LOSs) are virulence determinants of Glaesserella parasuis, a pathogen of the respiratory tract of pigs. We previously reported that disruption of the galU or galE gene in G. parasuis results in increased sensitivity to porcine serum, indicating that the
Guillermo Martín-Gutiérrez et al.
Antibiotics (Basel, Switzerland), 9(11) (2020-11-18)
Mutations that confer low-level fosfomycin resistance (LLFR) but not clinical resistance in Escherichia coli are increasingly reported. LLFR strains can become clinically resistant under urinary tract physiological conditions or may act as gateways for highly resistant subpopulations by the selection
Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice.
Virtu C N, et al.
The Journal of Biological Chemistry, 290, 15581-15594 (2015)
文章
沃伯格效應會增強腫瘤細胞中葡萄糖到乳酸的轉換，而不受氧氣水平的影響；自 1924 年起就開始影響癌症新陳代謝。
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
相關內容
Assay protocol for the colorimetric detection of glucose-6-phosphate in biological samples using the glucose-6-phosphate assay kit.
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