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Merck
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重要文件

M9005

Sigma-Aldrich

3-甲基-L-组氨酸

≥98% (TLC)

同義詞:

π-甲基-L-组氨酸, 1-甲基-L-组氨酸(不再使用), 3-(1-甲基咪唑-5-基)-L丙氨酸

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About This Item

經驗公式(希爾表示法):
C7H11N3O2
CAS號碼:
分子量::
169.18
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26
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產品名稱

3-甲基-L-组氨酸,

化驗

≥98% (TLC)

形狀

powder

顏色

white to off-white

mp

254 °C

應用

detection

SMILES 字串

Cn1cncc1C[C@H](N)C(O)=O

InChI

1S/C7H11N3O2/c1-10-4-9-3-5(10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1

InChI 密鑰

JDHILDINMRGULE-LURJTMIESA-N

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應用


  • Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.:研究创新基因工程技术,用组氨酸类似物(如3-甲基-L-组氨酸)制出功能改进的新蛋白。治疗和工业应用前景广阔(Taylor et al., 2023)。

  • Improving the enzymatic activity of l-amino acid α-ligase for imidazole dipeptide production by site-directed mutagenesis.:研究如何改进咪唑二肽的酶促合成。对于了解各种修饰(如3-甲基-L-组氨酸)的作用及其生物活性影响有重要意义(Kino et al., 2023)。

生化/生理作用

3-甲基-L-组氨酸是一种非蛋白原氨基酸,也是一项肌肉分解的指标。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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M N Goodman
The American journal of physiology, 260(5 Pt 1), E727-E730 (1991-05-01)
The metabolic response to infection includes loss of lean tissue and increased nitrogen excretion. The loss of muscle tissue during infection results in large part from accelerated skeletal muscle protein breakdown. Recent studies suggest that macrophage-derived products secreted during infection
E Roth et al.
Clinical chemistry, 31(8), 1305-1309 (1985-08-01)
We measured amino acid concentrations in plasma and skeletal muscle of three groups of patients with acute hemorrhagic pancreatitis: (a) patients without secondary organ lesions, (b) patients also suffering from kidney damage, and (c) patients in whom the pancreatitis was
Melanie J Edwards et al.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 180(2), 247-257 (2009-09-04)
We fed common brushtail possums artificial diets containing a buffer and the plant secondary metabolite (PSM), orcinol, to test the hypothesis that organic acids, common products of PSM metabolism, limit feeding by common brushtail possums (Trichosurus vulpecula). We introduced several
Elin Chorell et al.
Journal of proteome research, 8(6), 2966-2977 (2009-03-26)
We have investigated whether postexercise ingestion of carbohydrates in combination with proteins generates a different systemic metabolic response, as compared to the sole ingestion of carbohydrate or water, in the early recovery phase following exercise. In addition, metabolic patterns related
Rokhsareh F Vesali et al.
Clinical science (London, England : 1979), 118(6), 421-427 (2009-09-16)
The human endotoxin model has been used to study the early phase of sepsis. The aim of the present study was to assess leg muscle protein kinetics after an endotoxin challenge given to healthy human volunteers. Six healthy male subjects

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