This product is a mixture of heavy chain isoforms. Further identification of each has not been performed, however on electrophoresis gels, there is a primary band at approximately 200 kDa with a more faint, slightly lower molecular weight band present. This may indicate a higher concentration of MyHC I, however this has not been verified.
推薦產品
生物源
rabbit muscle
品質等級
形狀
buffered aqueous glycerol solution
技術
electrophoresis: suitable
UniProt登錄號
異物活動
ATPase Activity ≤0.01 units/mg protein
儲存溫度
−20°C
基因資訊
rabbit ... PBV1SPCR2(100009284)
一般說明
Myosin heavy chain (MHC) is a motor protein of muscle thick filaments. MHC regulates ultrastructural diversity of myofibrils.[1]
應用
Myosin Heavy Chain from rabbit muscle has been used:
- in SDS analysis of myosin heavy chain (MHC) composition and content[2]
- for microinjection into the outflow of heart (blood serum) and the cephalic cavities (embryonic cerebrospinal fluid) of chick embryo[3]
- as a muscle protein, to study the role of ascorbate as a facilitator of glycogen storage in muscles[4]
生化／生理作用
Molecular motor involved in the contraction of muscles.
外觀
Solution in 50% glycerol containing 0.6 M KCl and 0.005 M potassium phosphate, pH 6.5
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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The EMBO journal, 15(17), 4454-4459 (1996-09-02)
Myosin heavy chain (MHC) is the motor protein of muscle thick filaments. Most organisms produce many muscle MHC isoforms with temporally and spatially regulated expression patterns. This suggests that isoforms of MHC have different characteristics necessary for defining specific muscle
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Cardiac contraction is triggered by the cyclic interaction of the "molecular motor" protein myosin with the actin filament, consuming ATP as the energy source to produce tension or shortening. The myosin heavy chain (MHC) contains the actin- and ATP-binding sites
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Does M7659 product Myosin Heavy Chain from rabbit muscle consist of only one myosin heavy chain isoform or is it a mixture of isoforms? If it is a mixture, could you please provide additional information about its composition?
1 answer-
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