推薦產品
化驗
≥98% (HPLC)
形狀
powder
溶解度
1 M NaOH: 20 mg/mL, clear to slightly hazy
SMILES 字串
CN1C(=O)NC2=C(NC(=O)N2)C1=O
InChI
1S/C6H6N4O3/c1-10-4(11)2-3(9-6(10)13)8-5(12)7-2/h1H3,(H,9,13)(H2,7,8,12)
InChI 密鑰
QFDRTQONISXGJA-UHFFFAOYSA-N
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應用
1-甲基尿酸已用于：
- 通过液相色谱和串联质谱法测定粪便样品中的尿酸
- 合成尿液样品的比浊法
- 作为CYP1A2（细胞色素P450家族1亚家族A成员2）测定的底物
生化／生理作用
1-甲基尿酸（1-U）是咖啡因和茶碱的主要代谢产物，具有抗氧化活性，可保护诸如低密度脂蛋白（LDL）之类的分子免受氧化修饰。1-甲基尿酸可用于旨在区分咖啡因和茶碱代谢物活性的研究。
包裝
无底玻璃瓶。内含物装在插入的融合锥内。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Effects of peppermint tea consumption on the activities of CYP1A2, CYP2A6, Xanthine Oxidase, N-acetyltranferase-2 and UDP-glucuronosyltransferases-1A1/1A6 in healthy volunteers
Begas E, et al.
Food And Chemical Toxicology, 100, 80-89 (2017)
C Lee
Clinica chimica acta; international journal of clinical chemistry, 295(1-2), 141-154 (2000-04-18)
Although caffeine has been suggested as an antioxidant at millimolar concentrations, little information is available about the antioxidant activity of caffeine and its metabolites at physiological concentrations. Antioxidant activity was measured by oxygen-radical absorbing capacity (ORAC) using 2, 2'-azobis(2-amidinopropane) dihydrochloride
Theophano A Psarra et al.
Fundamental & clinical pharmacology, 22(5), 537-547 (2008-10-11)
The present study, aimed to clarify whether the gastrointestinal adverse effects following administration of the bronchodilator theophylline are owing to the action of the drug itself or its metabolites, investigates the pharmacodymanic effects of theophylline's metabolites on the spontaneous contractility
Xanthine urolithiasis: Inhibitors of xanthine crystallization
Grases F, et al.
bioRxiv, 335364-335364 (2018)
Klaus Abraham et al.
Clinical pharmacology and therapeutics, 72(2), 163-174 (2002-08-22)
The correct in vivo quantification of aryl hydrocarbon receptor-mediated induction of cytochrome P450 1A2 (CYP1A2) in humans is a long-standing question. We compared the performance of several modifications of the caffeine test for measurement of CYP1A2 activity in subjects with
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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