推薦產品
生物源
Escherichia coli
品質等級
重組細胞
expressed in E. coli
描述
200 amino acid residue methionyl form of mature, recombinant human prolactin (amino acid residues 29-227).
產品線
BioReagent
化驗
>97% (SDS-PAGE)
形狀
lyophilized powder
效力
0.030-0.300 ng/mL EC50
分子量
predicted mol wt ~24 kDa
技術
cell culture | mammalian: suitable
雜質
endotoxin, tested
溶解度
water: 0.5000 mL, clear, colorless
UniProt登錄號
運輸包裝
ambient
儲存溫度
−20°C
基因資訊
human ... PRL(5617)
應用
可用在细胞培养应用中研究催乳素对细胞信号传导和基因表达的调节。
生化／生理作用
催乳素是一种神经内分泌激素。催乳激素受体是一种跨膜糖蛋白，属于细胞因子造血受体家族。大量细胞和器官表达该受体，包括 B 细胞、T 细胞、巨噬细胞、单核细胞和嗜中性粒细胞。催乳素信号转导涉及 JAK/STAT 家族和 src 激酶家族。引起泌乳；抑制促性腺激素的分泌；释放受多巴胺抑制。
神经内分泌激素；属于细胞因子造血受体家族；诱导泌乳；抑制促性腺激素的分泌；释放受多巴胺抑制。
其他說明
包含天然产物中不存在的 N 末端甲硫氨酸。
外觀
从 10mM 磷酸盐和 50mM 氯化钠溶液（pH 8.0）中冻干。
重構
建议将无菌 4 mM HCl（含 1 mg/mL 牛血清白蛋白）添加到小瓶中，以制备不低于 100 μg/mL 的储液。
分析報告
生物学活性是通过大鼠淋巴瘤细胞系 Nb2-11 的增殖实验测定的。
訊號詞
Danger
危險聲明
危險分類
Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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分析證明 (COA)
Lot/Batch Number
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Journal of cellular physiology, 163(2), 221-231 (1995-05-01)
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