推薦產品
生物源
human epidermis
化驗
≥90% (SDS-PAGE)
形狀
urea solution
技術
ELISA: suitable
UniProt登錄號
儲存溫度
2-8°C
基因資訊
human ... KRT1(3848)
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一般說明
角蛋白是上皮组织的标志性中间纤维蛋白。在人类中，角蛋白分为I型和II型。约有54个基因编码角蛋白。角蛋白1（KRT1）基因被定位到人类染色体12q13.13上。它是头发、皮肤和指甲的主要成分。
應用
人表皮角蛋白已用于：
- 在固相抗体芯片中作为分析物和交叉反应剂用于测定选择系数
- 作为细胞外基质(ECM)蛋白标准品进行体外蛋白降解分析
- 作为酶联免疫吸附测定(ELISA)的标准品
生化／生理作用
角蛋白对于上皮细胞和组织的机械稳定性和完整性非常重要。一些角蛋白还具有调节功能，并可参与细胞内信号转导途径，例如对压力的保护、伤口愈合和细胞凋亡。这组多样化的细胞骨架支架蛋白可形成中等细丝网络，其为维持皮肤完整性的角质形成细胞提供了结构支持。角蛋白基因的表达通常受分层鳞状上皮细胞内表皮细胞分化的调节。
外觀
溶于 8 M 尿素、50 mM Tris、0.1 M β-巯基乙醇和 0.1% 叠氮化钠，pH 8.4
訊號詞
Warning
危險聲明
危險分類
Skin Sens. 1
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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