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Merck
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文件

J3955

Sigma-Aldrich

JTC-801

≥98% (HPLC)

同義詞:

N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide hydrochloride

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About This Item

經驗公式(希爾表示法):
C26H25N3O2 · HCl
CAS號碼:
分子量::
447.96
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

tan

溶解度

DMSO: ≥20 mg/mL

儲存溫度

2-8°C

SMILES 字串

Cl.CCc1ccc(OCc2ccccc2C(=O)Nc3ccc4nc(C)cc(N)c4c3)cc1

InChI

1S/C26H25N3O2.ClH/c1-3-18-8-11-21(12-9-18)31-16-19-6-4-5-7-22(19)26(30)29-20-10-13-25-23(15-20)24(27)14-17(2)28-25;/h4-15H,3,16H2,1-2H3,(H2,27,28)(H,29,30);1H

InChI 密鑰

NQLIYKXNAXKMBL-UHFFFAOYSA-N

生化/生理作用

JTC-801 is a nociceptin/orphanin FQ peptide (NOP) receptor antagonist.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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G Delaney et al.
Journal of neuroendocrinology, 24(12), 1527-1541 (2012-07-28)
Central nociceptin/orphanin FQ (N/OFQ)-expressing neurones are abundantly expressed in the hypothalamus and limbic system and are implicated in the regulation of activity of the hypothalamic-pituitary-adrenal axis (HPA) and stress responses. We investigated the role of the endogenous N/OFQ receptor (NOP)
Keiichi Hiramoto et al.
Photodermatology, photoimmunology & photomedicine, 33(2), 84-91 (2017-01-01)
We previously reported that ultraviolet (UV) A eye irradiation reduces the ulcerative colitis induced by dextran sodium sulfate (DSS). This study examined the effects of UVA on colon carcinoma induced by azoxymethane (AOM) and DSS. We irradiated the eyes of

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