推薦產品
生物源
goat
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
secondary antibodies
無性繁殖
polyclonal
形狀
lyophilized powder
技術
Ouchterlony double diffusion: suitable
儲存溫度
2-8°C
目標翻譯後修改
unmodified
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一般說明
IgG抗体亚型是免疫系统中含量最高的血清免疫球蛋白。它由B细胞分泌,存在于血液和细胞外液中,可防止细菌、真菌和病毒引起的感染。母体IgG通过胎盘传递至胎儿,对新生儿的感染免疫防御能力至关重要。人IgG(γ链特异性)抗体对所有人IgG亚类的γ链具有特异性。
免疫球蛋白(Ig)属于免疫球蛋白超家族,包含两条重链(H)和两条轻链(L),它们通过二硫键相连。L链包含一个可变N-末端区域和一个恒定C-末端区域。重链包有一个N-端可变区和三个或四个(CH1-CH4)C-端恒定区。IgG是人血清中含量最丰富的一种蛋白。IgG分为IgG1、IgG2、IgG3和IgG4四类。IgG重链区域定位于人类14号染色体。
免疫原
纯化人IgG
應用
人IgG(γ链特异性)抗体在ELISA和放射免疫分析中可作为对照品使用。
生化/生理作用
IgG1类是最丰富的,其缺乏会导致低丙球蛋白血症。IgG2缺乏会增加对细菌感染的易感性。IgG3介导效应子功能,IgG4与无症状感染有关。木瓜蛋白酶消化IgG导致产生片段抗原结合(Fab)。IgG的胃蛋白酶消化形成可结晶的片段(Fc)。IgG抗体的Fc区具有巨大的治疗潜力,可用于开发治疗性抗体。
外觀
0.01 mM 磷酸钠,0.015 mM 氯化钠,pH 7.2
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
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