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About This Item
經驗公式（希爾表示法）:
C17H16FN5O7S · HCl
CAS號碼:
分子量：:
489.86
Beilstein:
8178939
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51
推薦產品
生物源
synthetic (organic)
化驗
≥95% (TLC)
形狀
powder
溶解度
methanol: 50 mg/mL, clear, colorless
儲存溫度
−20°C
SMILES 字串
Cl[H].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COC(=O)c4ccc(cc4)S(F)(=O)=O)[C@@H](O)[C@H]3O
InChI
1S/C17H16FN5O7S.ClH/c18-31(27,28)9-3-1-8(2-4-9)17(26)29-5-10-12(24)13(25)16(30-10)23-7-22-11-14(19)20-6-21-15(11)23;/h1-4,6-7,10,12-13,16,24-25H,5H2,(H2,19,20,21);1H/t10-,12-,13-,16-;/m1./s1
InChI 密鑰
ZUHVYHQVJYIHPN-KHXPSBENSA-N
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應用
5′-（4-氟磺酰基苯甲酰基）腺苷盐酸盐可用于与 Ime2（减数分裂 2 的诱导剂）孵育以确定 Ime2 对三磷酸腺苷（ATP）类似物 5′-氟磺酰基苯甲酰腺苷（FSBA）的敏感性。
5′-（4-氟磺酰基苯甲酰基）腺苷（FSBA）是 ATP 类似物，用于研究渥曼青霉素的作用机理。FSBA 已用于研究肠道细胞（例如 Caco-2）中的囊泡运输，并对各种 ATP 酶、激酶和其他蛋白质的核苷酸结合域（NBD）中的残基进行共价修饰。
生化／生理作用
由于 5′-（4-氟磺酰基苯甲酰基）腺苷与这些基序中发生的亲核氨基酸反应，因此其有助于识别激酶中的三磷酸腺苷（ATP）结合位点。
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Giovanni Renzone et al.
Proteins, 67(1), 189-197 (2007-01-24)
Sso7d from the extreme thermophilic crenarchaeon Sulfolobus solfataricus is a multifunctional protein in in vitro assays, whose in vivo role is still puzzling. Crystals of Sso7d in complex with DNA elucidated the protein surface involved in the binding to the
Kenichi A Tanaka et al.
Platelets, 15(5), 325-332 (2004-09-17)
The use of clopidogrel (Plavix), an inhibitor of adenosine diphosphate (ADP)-induced platelet aggregation, has been proven to reduce ischemic events in cardiovascular patients, but little information is available for optimal monitoring of platelet function in patients receiving the drug preoperatively.
Steven J Ratcliffe et al.
Journal of biomolecular screening, 12(1), 126-132 (2006-12-15)
Most of the kinase inhibitors that are approved for therapeutic uses or that are undergoing clinical trials are directed toward the adenosine triphosphate (ATP) binding site of protein kinases. 5'-Fluorosulfonylbenzoyl 5'-adenosine (FSBA) is an activitybased probe (ABP) that covalently modifies
Nicolas Menzel et al.
Analytical biochemistry, 368(2), 178-184 (2007-06-29)
Nearly all processes in cells are regulated by the coordinated interplay between reversible protein phosphorylation and dephosphorylation. Therefore, it is a great challenge to identify all phosphorylation substrates of a single protein kinase to understand its integration into intracellular signaling
Eric Faudry et al.
The Journal of biological chemistry, 279(19), 19607-19613 (2004-02-27)
Apyrases are nucleoside triphosphate-diphosphohydrolases (EC 3.6.1.5) present in a variety of organisms. The apyrase activity found in the saliva of hematophagous insects is correlated with the prevention of ADP-induced platelet aggregation of the host during blood sucking. Purification of apyrase
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