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文件

F1016

Sigma-Aldrich

非诺特罗 氢溴酸盐

同義詞:

2-(3,5-Dihydroxyphenyl)-2-hydroxy-2′-(4-hydroxyphenyl)-1′-methyldiethylamine hydrobromide

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About This Item

經驗公式(希爾表示法):
C17H21NO4 · HBr
CAS號碼:
分子量::
384.26
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77

起源

Boehringer Ingelheim

SMILES 字串

Br[H].CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2

InChI

1S/C17H21NO4.BrH/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13;/h2-5,7-9,11,17-22H,6,10H2,1H3;1H

InChI 密鑰

SGZRQMALQBXAIQ-UHFFFAOYSA-N

基因資訊

human ... ADRB2(154)

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一般說明

Fenoterol hydrobromide is a sympathomimetic drug. It is used to treat asthma, bronchitis and emphysema. Fenoterol administration might be linked to liver damage. It has anti-inflammatory effects on eosinophil function.

應用

Fenoterol hydrobromide has been used in chromatography-tandem mass spectrometry (LC&-MS-MS) for specific and sensitive detection of β-agonists (BAG).

生化/生理作用

β2-adrenoceptor agonist; bronchodilator.

特點和優勢

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Julia J Rucklidge et al.
Human psychopharmacology, 27(5), 440-454 (2012-07-12)
To compare two micronutrient (vitamins and minerals) formulas (Berocca™ and CNE™) and assess their impact on emotions and stress related to the 6.3 earthquake on February 22(nd) 2011 in Christchurch, New Zealand. 91 adults experiencing heightened anxiety or stress 2-3 months
Lawrence Toll et al.
Molecular pharmacology, 81(6), 846-854 (2012-03-22)
G protein-coupled receptors (GPCRs) are integral membrane proteins that change conformation after ligand binding so that they can transduce signals from an extracellular ligand to a variety of intracellular components. The detailed interaction of a molecule with a G protein-coupled
Krzysztof Jozwiak et al.
Chirality, 23 Suppl 1, E1-E6 (2011-05-28)
The β(2) adrenergic receptor (β(2)-AR) is a model system for studying the ligand recognition process in G protein-coupled receptors. Fenoterol (FEN) is a β(2)-AR selective agonist that has two centers of chirality and exists as four stereoisomers. Radioligand binding studies
Rajib K Paul et al.
The Journal of pharmacology and experimental therapeutics, 343(1), 157-166 (2012-07-11)
Inhibition of cell proliferation by fenoterol and fenoterol derivatives in 1321N1 astrocytoma cells is consistent with β(2)-adrenergic receptor (β(2)-AR) stimulation. However, the events that result in fenoterol-mediated control of cell proliferation in other cell types are not clear. Here, we
Oxford Dictionary of Medicines, Jan Hawthorn, 2003: Oxford Dictionary of Medicines (2003)

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