EPS001
HAT Activator, CTPB
A potent activator of HAT (histone acetyltransferase)
同義詞:
Benzamide, N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl, CTPB, CTPB (enzyme activator), CTPB (enzyme inhibitor), N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide
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About This Item
暫時無法取得訂價和供貨情況
推薦產品
化驗
≥97% (H-NMR)
儲存條件
desiccated
protect from light
顏色
white to off-white
溶解度
DMSO: soluble
儲存溫度
−20°C
InChI
1S/C31H43ClF3NO2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-18-24-19-17-20-28(38-4-2)29(24)30(37)36-25-21-22-27(32)26(23-25)31(33,34)35/h17,19-23H,3-16,18H2,1-2H3,(H,36,37)
InChI 密鑰
OYBMVMAXKOGYDC-UHFFFAOYSA-N
一般說明
(N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide) or CTPB, which is a non-polar compound, has been shown to enhance the neurite growth and survival of neuronal cell lines.[1][2]
A potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
A small molecule activator of p300/CBP histone acetyltransferase promotes survival and neurite growth in a cellular model of Parkinson?s disease
Shane VH et al.
Neurotoxicity Research, 30(3), 510-520 (2016)
Small molecule modulators of histone acetyltransferase p300
Karanam B et al.
The Journal of Biological Chemistry (2003)
Shufeng Li et al.
OncoTargets and therapy, 13, 12383-12395 (2020-12-11)
Cervical squamous cell carcinoma (CSCC) is responsible for 80-85% of cervical cancer. Cyclin B1 (CCNB1) represents a hub gene during the development of cervical cancer. However, the oncogenic role of CCNB1 in CSCC remains unclear. Our study aims to explore
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