推薦產品
生物源
microbial
形狀
solid
效力
≥780 μg per mg
顏色
white
溶解度
ethanol: 50 mg/mL
抗生素活性譜
Gram-positive bacteria
作用方式
protein synthesis | interferes
SMILES 字串
CCOC(=O)CCC(=O)OC1C(CC(C)OC1OC2C(C)C(OC3CC(C)(OC)C(O)C(C)O3)C(C)C(=O)OC(CC)C(C)(O)C(O)C(C)C(=O)C(C)CC2(C)O)N(C)C
InChI
1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3
InChI 密鑰
NSYZCCDSJNWWJL-UHFFFAOYSA-N
尋找類似的產品？ 前往 產品比較指南
一般說明
Chemical structure: macrolide
應用
Erythromycin ethyl succinate is used to study erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae[1]. It has been used to study down-regulation of motilin receptors on rabbit colon myocytes[2] and lethal mutations in outer membrane genes omsA and firA in Salmonella typhimurium[3].
生化／生理作用
Erythromycin inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site) by binding to the 50s subunit of the bacterial 70s rRNA complex.
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
S D Bologna et al.
The Journal of pharmacology and experimental therapeutics, 266(2), 852-856 (1993-08-01)
Acutely, erythromycin stimulates colonic smooth muscle contraction via action on motilin receptors, but the effects of chronic erythromycin exposure are unknown. Thus contraction and motilin binding studies were performed on rabbit colonic smooth muscle after 2 weeks of oral erythromycin
R Vuorio et al.
Journal of bacteriology, 174(22), 7090-7097 (1992-11-01)
We have previously identified the gene (the ssc gene) defective in the thermosensitive and antibiotic-supersusceptible outer membrane permeability mutant SS-C of Salmonella typhimurium and shown that this gene is analogous to the Escherichia coli gene firA (L. Hirvas, P. Koski
A Deicke et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 49(1), 73-78 (1999-12-30)
The content of active ingredient of single doses of a suspension depends to a large extent upon the redispersibility of the product. Mathematical and technical aspects of a procedure to test this property have been discussed in a preceding article.
Nawal El-Rabbat et al.
Journal of AOAC International, 89(5), 1276-1287 (2006-10-18)
This paper describes a simple spectrofluorometric method for the analysis of 4 macrolide antibiotics. The method is based on the condensation of 10% (w/v) malonic acid and acetic acid anhydride under the catalytic effect of tertiary amine groups of the
Yan-Chun Feng et al.
Journal of pharmaceutical and biomedical analysis, 41(2), 373-384 (2006-01-13)
Universal quantitative models using NIR reflectance spectroscopy were developed for the analysis of API contents (active pharmaceutical ingredient) in roxithromycin and erythromycin ethylsuccinate tablets from different manufacturers in China. The two quantitative models were built from 78 batches of roxithromycin
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