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重要文件

D6513

Sigma-Aldrich

去氢胆甾醇

≥84% (GC)

同義詞:

24-去氢胆甾醇, 3β-羟基-5,24-胆甾二烯, 5,24-胆甾二烯-3β-ol

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About This Item

經驗公式(希爾表示法):
C27H44O
CAS號碼:
分子量::
384.64
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
暫時無法取得訂價和供貨情況

化驗

≥84% (GC)

形狀

powder

儲存溫度

−20°C

SMILES 字串

[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC=C(C)C

InChI

1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI 密鑰

AVSXSVCZWQODGV-DPAQBDIFSA-N

相關類別

一般說明

链甾醇是胆固醇合成中C27甾醇的中间体。它可能与阿尔茨海默病′(AD)的发病机制有关。[1]

應用

链甾醇已被用作估计胆固醇和植物甾醇浓度的标准品。[2][3]此外,也可用于抑制尼日尔素诱导的固醇调节元件结合蛋白2 (SREBP2)的成熟。[4]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Journal of functional foods, 21, 97-103 (2016)
Clare L Beasley et al.
Bipolar disorders, 7(5), 449-455 (2005-09-24)
Cholesterol forms an integral part of cell membranes and is a major component of myelin. Furthermore, cholesterol also plays a vital role in the development, function and stability of synapses. While low serum cholesterol has previously been associated with mood
Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
Guo C, et al.
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Prostate cancer (PCa) is an important health problem worldwide. Diagnosis and management of PCa is very complex because the detection of serum prostate specific antigen (PSA) has several drawbacks. Metabolomics brings promise for cancer biomarker discovery and for better understanding

文章

Cholesterol biosynthesis starts in the hepatic endoplasmic reticulum with acetyl-CoA, yielding 3-hydroxy-3-methylglutaryl-CoA via HMG-CoA synthase.

膽固醇的生物合成始於肝內質網中的乙酰-CoA,經由 HMG-CoA 合成酶產生 3-羥基-3-甲基戊二酰-CoA。

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