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D2569

Sigma-Aldrich

Anti-DPPA5 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-Developmental pluripotency associated 5, Anti-ESG1, Anti-Embryonal stem cell-specific gene 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
暫時無法取得訂價和供貨情況

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~14 kDa

物種活性

mouse, human, rat

濃度

~1 mg/mL

技術

immunohistochemistry: 1:100-1:250
western blot: 1:500-1:1,000

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

一般說明

The DPPA5 (developmental pluripotency associated 5) protein is strongly expressed in primordial germ cells, and the expression is down-regulated during germ cell development.

免疫原

synthetic peptide corresponding to residues 43-60 human DPPA5. The sequence is 85% identical in mouse and rat.

應用

Anti-DPPA5 antibody produced in rabbit is suitable for immunohistochemistry at a working dilution of 1:100 to 1:250 and for immunoblotting at 1:500 to 1:1000.

生化/生理作用

DPPA5 is specifically and differentially expressed in human cells that have pluripotency and can be used as a marker of pluripotent stem cells.

外觀

solution in phosphate buffered saline, containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Soo-Kyoung Kim et al.
Stem cells (Dayton, Ohio), 23(4), 458-462 (2005-03-26)
Pluripotent embryonic germ cells (EGCs) can be derived from the culture of primordial germ cells (PGCs). However, there are no reports of gonocytes, following the stage of PGC development, becoming stem cell lines. To analyze the gene expression differences between
Ida M A Jentoft et al.
Cell, 186(24), 5308-5327 (2023-11-06)
Mammalian oocytes are filled with poorly understood structures called cytoplasmic lattices. First discovered in the 1960s and speculated to correspond to mammalian yolk, ribosomal arrays, or intermediate filaments, their function has remained enigmatic to date. Here, we show that cytoplasmic
Shichao Liu et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 244(4), 619-627 (2015-01-27)
Mammalian first lineage segregation generates trophectoderm (TE) and pluripotent inner cell mass (ICM), which provides an ideal model for studying the mechanisms of maintenance and loss of pluripotency. In mouse, the transcription factor OCT4 restricts to ICM and plays a

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