推薦產品
形狀
powder
技術
ligand binding assay: suitable
儲存溫度
−20°C
SMILES 字串
CN(C)c1cccc2c(cccc12)S(=O)(=O)NCC(O)=O
InChI
1S/C14H16N2O4S/c1-16(2)12-7-3-6-11-10(12)5-4-8-13(11)21(19,20)15-9-14(17)18/h3-8,15H,9H2,1-2H3,(H,17,18)
InChI 密鑰
QHFXORCWAQTTGH-UHFFFAOYSA-N
應用
Dansylglycine, an HSA drug site II probe, is used for the differentiation and analysis of specific binding sites on serum albumin. Dansylglycine is used to generate chromophore-modified cyclodextrins for use in chemosensor development.
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
R Yajima et al.
Journal of chromatography. B, Biomedical applications, 667(2), 333-338 (1995-05-19)
A rapid and sensitive high-performance liquid chromatographic (HPLC)-fluorimetric assay method has been developed for the determination of carboxypeptidase H activity based on the measurement of N-(5-dimethyl-aminonaphthalene-1-sulfonyl)glycine (dansyl-Gly) formed enzymatically from dansyl-Gly-L-Lys or dansyl-Gly-L-Arg. Dansyl-Gly is eluted faster than the substrates
T J Dengler et al.
European journal of clinical pharmacology, 43(5), 491-499 (1992-01-01)
The binding capacity of human serum albumin (HSA) for small acidic molecules is known to be reduced in chronic renal failure (CRF). The contribution of competitive inhibition by accumulated endogenous ligands and of structural changes in HSA has now been
T Tanabe et al.
Analytical chemistry, 73(13), 3126-3130 (2001-07-27)
Dansylglycine-modified cyclodextrin (DnsC4-beta-CD) was prepared as a fluorescent host that is capable of being immobilized on a cellulose membrane (DnsC4-beta-CD membrane). DnsC4-beta-CD immobilized on the cellulose membrane decreased its fluorescence intensity with increasing concentration of guest molecules, indicating that the
Eva A Enyedy et al.
Bioorganic & medicinal chemistry, 19(14), 4202-4210 (2011-06-24)
The specific binding of carrier ligands of antidiabetic vanadium(IV) and zinc(II) complexes into drug binding pockets of human serum albumin (HSA) has been investigated via displacement reactions of site markers such as warfarin and dansylglycine by different spectroscopic (fluorescence, circular
J Bramhall
Biochemistry, 25(13), 3958-3962 (1986-07-01)
The amphiphilic fluorescent dye N-[(5-dimethylamino)naphth-1-ylsulfonyl]glycine (dansylglycine) can be used to monitor the magnitude and stability of transmembrane proton gradients. Although freely soluble in aqueous media, the dye readily adsorbs to the surfaces of lipid vesicles. Because membrane-bound dye fluoresces at
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