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重要文件

425311

Sigma-Aldrich

IR-780 碘

Dye content ≥95 %

同義詞:

2-[2-[2-氯-3-[(1,3-二氢-3,3-二甲基-1-丙基-2H-吲哚-2-亚基)亚乙基]-1-环己烯-1-基]乙烯基]-3,3-二甲基-1-丙基吲哚鎓碘化物

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About This Item

經驗公式(希爾表示法):
C36H44ClIN2
CAS號碼:
分子量::
667.11
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.23
暫時無法取得訂價和供貨情況

形狀

solid

品質等級

成份

Dye content, ≥95%

mp

232-234 °C (lit.)

λmax

780 nm

SMILES 字串

[I-].CCCN1c2ccccc2C(C)(C)/C1=C\C=C3/CCCC(\C=C\C4=[N+](CCC)c5ccccc5C4(C)C)=C3Cl

InChI

1S/C36H44ClN2.HI/c1-7-24-38-30-18-11-9-16-28(30)35(3,4)32(38)22-20-26-14-13-15-27(34(26)37)21-23-33-36(5,6)29-17-10-12-19-31(29)39(33)25-8-2;/h9-12,16-23H,7-8,13-15,24-25H2,1-6H3;1H/q+1;/p-1

InChI 密鑰

IRPKBYJYVJOQHQ-UHFFFAOYSA-M

一般說明

IR-780碘化物是一种近红外亲脂性阳离子七甲胺荧光染料。它具有良好的荧光强度,可用作光热疗法治疗剂。这种成分表现出了780 nm的光吸收光谱,因而在医学治疗应用中被用作声动力学治疗剂。[1][2][3]

應用

基于IR-780的染料有望用于生物医学应用和药物递送,支持肿瘤成像和靶向治疗。[4][5]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

IR-780 dye as a sonosensitizer for sonodynamic therapy of breast tumor
Li Y, et al.
Scientific Reports, 6(28), 25968-25968 (2016)
IR-780 dye for near-infrared fluorescence imaging in prostate cancer
Yi X, et al.
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 21(28), 511-511 (2015)
IR-780 dye loaded tumor targeting theranostic nanoparticles for NIR imaging and photothermal therapy
Yue C, et al.
Biomaterials, 34(28), 6853-6861 (2013)
Sentinel lymph node mapping by a near-infrared fluorescent heptamethine dye
Zhang C, et al.
Biomaterials, 31(7), 1911-1917 (2010)
Preferential accumulation of the near infrared heptamethine dye IR-780 in the mitochondria of drug-resistant lung cancer cells
Wang Y, et al.
Biomaterials, 35(13), 4116-4124 (2014)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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