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C6506

Sigma-Aldrich

4-氯-DL-苯丙氨酸

greener alternative

同義詞:

PCP, PCPA

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About This Item

線性公式:
ClC6H4CH2CH(NH2)CO2H
CAS號碼:
7424-00-2
分子量：:
199.63
EC號碼:
231-051-9
MDL號碼:
MFCD00002601
分類程式碼代碼:
12352209
PubChem物質ID:
24278081
NACRES:
NA.32

形狀

solid

環保替代產品評分

old score: 2
new score: 1
Find out more about DOZN™ Scoring

環保替代產品特色

Less Hazardous Chemical Syntheses
Designing Safer Chemicals
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

>240 °C (dec.) (lit.)

環保替代類別

, Re-engineered

儲存溫度

room temp

SMILES 字串

NC(Cc1ccc(Cl)cc1)C(O)=O

InChI

1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)

InChI 密鑰

NIGWMJHCCYYCSF-UHFFFAOYSA-N

基因資訊

human ... TPH1(7166) , TPH2(121278)

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相關類別

一般說明

我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。本品属于重新设计产品类别，在“危险性较小的化学合成”、“设计更安全的化学品和产品”和“节能设计”绿色化学原则方面取得了重大改进。 点击此处查看其 DOZN 记分卡。

應用

4-氯-DL-苯丙氨酸用于：
  • 作为色氨酸羟化酶1（TPH1）抑制剂，处理 kras+ 雄性斑马鱼
  • 在大鼠模型中诱发失眠
  • 处理胚胎，检查其对5-羟色胺的影响
  • 选择带 pESentA32质粒的粪肠球菌（ Enterococcus faecalis ）转化体
  • 饲喂苍蝇，研究5-羟色胺的作用

生化／生理作用

4-氯-DL-苯丙氨酸（PCPA）是5-羟色胺（5-HT）合成抑制剂。有助于改善肺部组织炎症和重塑肺动脉。PCPA 可减少色氨酸羟化酶1（TPH1）、基质金属蛋白酶（MMP）和促炎因子的表达。
色氨酸羟化酶抑制剂。

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301,H317

危險分類

Acute Tox. 3 Oral - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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