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Merck
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文件

C4479

Sigma-Aldrich

9-Cyclopentyladenine monomethanesulfonate

≥98% (HPLC)

同義詞:

9-CP-Ade mesylate, 9-Cyclopentyladenine mesylate

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About This Item

線性公式:
C10H13N5 · CH3SO3H
CAS號碼:
分子量::
299.35
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

mp

180-183 °C (lit.)

溶解度

H2O: 5 mg/mL, clear

儲存溫度

room temp

SMILES 字串

CS(O)(=O)=O.Nc1ncnc2n(cnc12)C3CCCC3

InChI

1S/C10H13N5.CH4O3S/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-7;1-5(2,3)4/h5-7H,1-4H2,(H2,11,12,13);1H3,(H,2,3,4)

InChI 密鑰

AJMDRSJHCYQPQI-UHFFFAOYSA-N

生化/生理作用

A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain. IC50 = 100 μM in detergent-dispersed rat brain preparation.

特點和優勢

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Yu Zhang et al.
Frontiers in neuroscience, 14, 364-364 (2020-05-16)
Electrical synapses between neurons exhibit a high degree of plasticity, which makes critical contributions to neuronal communication. The GABAergic parvalbumin-expressing (PV+) neurons in the thalamic reticular nucleus (TRN) interact with each other through electrical and chemical synapses. Plasticity of electrical

文章

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

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