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A6655

Sigma-Aldrich

Aflatoxin B₁−BSA Conjugate

from Aspergillus flavus, powder, hepatotoxic mycotoxin

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.77

product name

黄曲霉毒素B1−BSA共轭物 来源于黄曲霉,

形狀

powder

品質等級

標籤範圍

8-12 mol Aflatoxin B1 per mol BSA

儲存溫度

2-8°C

一般說明

Aflatoxin B1 is the most toxic aflatoxin. Aflatoxins are hepatotoxic metabolites, that are produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins contaminate human food and animal feed. They are linked to liver cancer, immune system suppression, reduced growth rates, losses in feed efficiency and death. They are naturally found toxic carcinogens and the most widely known mycotoxins. They mainly contaminate fruits, vegetables and grains.

應用

Aflatoxin B1 is a carcinogenic compound that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene.
Aflatoxin B1-BSA Conjugate from Aspergillus flavus has been used in immunization of mice with phage and synthetic peptide. It is also used as a target molecule in si field-effect transistor (FET) biosensing techniques.

警告

可能致癌。

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


分析證明 (COA)

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Detection of uncharged or feebly charged small molecules by field-effect transistor biosensors
Ah CS, et al.
Biosensors And Bioelectronics, 33(1), 233-240 (2012)
Morvarid Karamkhani et al.
Environmental monitoring and assessment, 192(7), 472-472 (2020-07-02)
Many workers are exposed to health problems arising from molds, fungi, and their toxins during waste processing. Aflatoxin B1 (AFB1) level in airborne and settled dust, aflatoxin B1-albumin (AFB1-Alb) adduct in serum, liver and kidney biochemical tests, and body redox
Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2008)
Review of past and present research on Aflatoxin in Uganda
Kaaya NA and Warren HL
African Journal of Food, Agriculture, Nutrition and Development, 5(1), 425-428 (2005)
P Sizaret et al.
Journal of the National Cancer Institute, 69(6), 1375-1381 (1982-12-01)
Rabbit (outbred albino New Zealand White) antisera have been raised against aflatoxin B1 (AFB1) using as immunogen conjugates in which the hapten was coupled to bovine serum albumin (BSA) either through C1 or C8 with the oxime and the dichloride

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