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Merck
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A6412

Sigma-Aldrich

黄曲霉毒素M–BSA共轭物

同義詞:

AFM1-BSA conjugate

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About This Item

MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

形狀

powder

品質等級

標籤範圍

4-8 mol aflatoxin M1 per mol BSA (Lowry)

儲存溫度

2-8°C

一般說明

Aflatoxin M1 is a hydroxylated metabolite ofaflatoxin B1. It is found in milk secreted by mammary glands of lactatinganimals, humans, and milk products.

應用

Aflatoxin M1–BSA Conjugate has been used in the indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) with non-labeled aflatoxin M1 and anti-AFM1 antibody.

生化/生理作用

Aflatoxin M1 is a mycotoxin that elicits both hepatotoxic and hepatocarcinogenic effects leading to immunosuppression in animals. The bioconjugate of aflatoxin M1 (AFM1) with bovine serum albumin (BSA) is useful in the generation of AFM1 specific antibodies which may have immunoassay applications.

警告

可能致癌。

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


分析證明 (COA)

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K Thirumala-Devi et al.
Journal of agricultural and food chemistry, 50(4), 933-937 (2002-02-07)
High-titer rabbit polyclonal antibodies to aflatoxin M(1) (AFM1) were produced by utilizing AFM1-bovine serum albumin (BSA) conjugate as an immunogen. An indirect competitive enzyme-linked immunosorbent assay was standardized for estimating AFM1 in milk and milk products. To avoid the influence
Aflatoxin M1 in milk and dairy products, occurrence and recent challenges: A review
Iqbal S Z, et al.
Trends in Food Science & Technology, 46 (1) (2015)
Fatemeh Khademi et al.
Jundishapur journal of microbiology, 8(4), e16850-e16850 (2015-06-03)
Aflatoxins are the most extensively studied group of mycotoxins produced by molds, especially the Aspergillus group, which are highly toxic to animals and humans. Since immunoassay is a simple and rapid method for the analysis of many toxic substances in
A Radoi et al.
Talanta, 77(1), 138-143 (2008-09-23)
Five different clones of antibodies developed against the aflatoxin M(1) were investigated by using the classical indirect and direct competitive Enzyme-Linked Immunosorbent Assay (ELISA) formats, and also the direct competitive ELISA based on the use of the superparamagnetic nanoparticles. The
Pradeep Kumar et al.
Frontiers in microbiology, 7, 2170-2170 (2017-02-02)
The aflatoxin producing fungi, Aspergillus spp., are widely spread in nature and have severely contaminated food supplies of humans and animals, resulting in health hazards and even death. Therefore, there is great demand for aflatoxins research to develop suitable methods

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