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文件

A5656

Sigma-Aldrich

(±)-毒藜碱

≥90% (TLC), liquid

同義詞:

3-(2-哌啶基)吡啶, 新烟碱

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About This Item

經驗公式(希爾表示法):
C10H14N2
CAS號碼:
分子量::
162.23
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

化驗

≥90% (TLC)

形狀

liquid

光學活性

[α]25/D 0°, c = 1 in H2O(lit.)

顏色

colorless to yellow

轉變溫度

freezing point 9 °C

溶解度

H2O: 10 mg/mL
ethanol: 50 mg/mL

密度

1.05 g/mL at 25 °C (lit.)

應用

agriculture
environmental

SMILES 字串

C1CCC(NC1)c2cccnc2

InChI

1S/C10H14N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8,10,12H,1-2,5,7H2

InChI 密鑰

MTXSIJUGVMTTMU-UHFFFAOYSA-N

基因資訊

生化/生理作用

烟叶生物碱;烟碱型乙酰胆碱受体的强效激动剂。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

199.4 °F - closed cup

閃點(°C)

93 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


分析證明 (COA)

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W R Kem et al.
The Journal of pharmacology and experimental therapeutics, 283(3), 979-992 (1998-02-12)
We assessed the pharmacological activity of anabaseine, a toxin found in certain animal venoms, relative to nicotine and anabasine on a variety of vertebrate nicotinic receptors, using cultured cells, the Xenopus oocyte expression system, contractility assays with skeletal and smooth
M J Parker et al.
Molecular pharmacology, 54(6), 1132-1139 (1998-12-18)
We used equilibrium binding analysis to characterize the agonist binding properties of six different rat neuronal nicotinic receptor subunit combinations expressed in Xenopus laevis oocytes. The alpha4beta2 receptor bound [3H]cytisine with a Kdapp of 0.74 +/- 0. 14 nM. The
P M Gocze et al.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 13(4), 266-272 (1999-10-26)
To reveal the well known effect of smoking on the incidence of early abortion, the possible effects of cigarette alkaloids on progesterone and estradiol synthesis were investigated. A suspected cause for early spontaneous abortion is corpus luteum insufficiency. The present
N Mizrachi et al.
Journal of forensic sciences, 45(3), 736-741 (2000-06-16)
Death of a worker occurred after ingestion of unknown amounts of Nicotiana glauca G leaves. The leaves were cooked after having been mistakenly considered to be spices of a type which grow in Thailand. After ingestion, two Thai workers collapsed
Y Lu et al.
The Journal of pharmacology and experimental therapeutics, 291(3), 1127-1134 (1999-11-24)
Several neurochemical and electrophysiological studies have shown that neuronal nicotinic receptors are desensitized by pretreatment with lower agonist concentrations than are required to activate the receptors, but the extent of desensitization and agonist concentration required to produce desensitization vary depending

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