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About This Item
經驗公式（希爾表示法）:
C14H24N2O7 · 2HCl · 5H2O
CAS號碼:
分子量：:
495.35
Beilstein:
5684150
EC號碼:
MDL號碼:
分類程式碼代碼:
51101500
PubChem物質ID:
推薦產品
生物源
synthetic
化驗
≥98.0% (AT)
形狀
solid
顏色
white
溶解度
H2O: 50 mg/mL, clear, faintly yellow
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
作用方式
protein synthesis | interferes
儲存溫度
2-8°C
SMILES 字串
Cl[H].Cl[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]3([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]3([H])O2
InChI
1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
InChI 密鑰
DCHJOVNPPSBWHK-UXXUFHFZSA-N
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一般說明
Chemical structure: aminoglycoside
應用
Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.
注意
Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.
準備報告
Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.
其他說明
Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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D Moazed et al.
Nature, 327(6121), 389-394 (1987-06-04)
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We have isolated and characterized in vitro mutants of the Lyme disease agent Borrelia burgdorferi that are resistant to spectinomycin, kanamycin, gentamicin, or streptomycin, antibiotics that target the small subunit of the ribosome. 16S rRNA mutations A1185G and C1186U, homologous
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