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Merck
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重要文件

74558

Sigma-Aldrich

Methyl 4-nitrophenyl hexylphosphonate

≥95.0% (HPLC)

同義詞:

Hexylphosphonic acid methyl 4-nitrophenyl ester

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About This Item

經驗公式(希爾表示法):
C13H20NO5P
CAS號碼:
分子量::
301.28
Beilstein:
21690211
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
暫時無法取得訂價和供貨情況

化驗

≥95.0% (HPLC)

形狀

liquid

儲存溫度

−20°C

SMILES 字串

O=P(OC)(CCCCCC)OC1=CC=C([N+]([O-])=O)C=C1

InChI

1S/C13H20NO5P/c1-3-4-5-6-11-20(17,18-2)19-13-9-7-12(8-10-13)14(15)16/h7-10H,3-6,11H2,1-2H3

InChI 密鑰

RMJQAOXPKANPMM-UHFFFAOYSA-N

應用

This lipase suicide inhibitor can be utilized to determine lipase and hydrolase activity, even in complex protein mixtures. The molar amount of enzyme can be determined by active site titration experiments. The inhibitor is soluble in both DMF and DMSO. Active site titrations should be performed in a pH range from 7-8 considering that higher pH values can lead to appreciable spontaneous hydrolysis. It is recommended to perform corresponding negative controls (buffer only).

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Racemase activity of B. cepacia lipase leads to dual-function asymmetric dynamic kinetic resolution of α-aminonitriles.
Pornrapee Vongvilai et al.
Angewandte Chemie (International ed. in English), 50(29), 6592-6595 (2011-06-03)
G Zandonella et al.
European journal of biochemistry, 262(1), 63-69 (1999-05-07)
Fluorescent triacylglycerol analogs were synthesized as covalent inhibitors of lipase activity. The respective 1(3), 2-O-dialkylglycero-3(1)-alkyl-phosphonic acid p-nitrophenyl esters contain a fluorescent pyrenealkyl chain and a long-chain alkyl residue bound to the sn-2 and sn-1(3) positions of glycerol, respectively. The phosphonic
Nobuhiko Tokuriki et al.
Nature communications, 3, 1257-1257 (2012-12-06)
Optimization processes, such as evolution, are constrained by diminishing returns-the closer the optimum, the smaller the benefit per mutation, and by tradeoffs-improvement of one property at the cost of others. However, the magnitude and molecular basis of these parameters, and

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