推薦產品
生物源
bovine blood
化驗
≥90% (SDS-PAGE)
形狀
powder
品質
2×cryst.
lyophilized
分子量
Mr ~64500
技術
UV/Vis spectroscopy: suitable
雜質
salt, none detected
~0.3% Fe
損耗
≤8% loss on drying
儲存溫度
2-8°C
基因資訊
cow ... HBA1(281221) , HBB(280813) , HBE2(513240) , HBE4(513108) , HBG(511735) , alpha globin(512439)
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一般說明
Hemoglobin (Hb) is the protein responsible for storage and transport of oxygen and other gaseous ligands in red blood cells (RBC). Hb is also the pioneer material for synthesis of Hb-based oxygen carriers (HBOCs) that can be used as substitutes for RBC.
應用
α-弹性蛋白的溶解度已被应用于弹性蛋白模拟生物材料的构建。
生化／生理作用
氧气转运蛋白。Fe2+/Fe3+平衡是血液氧合的一种生理指标；脱氧血红蛋白通过将亚硝酸还原为NO来补充反馈回路，而NO是一种可增强血液流向缺氧组织流量的血管扩张剂。
氧转运体，NO 清除剂
注意
由于天然血红蛋白在空气中易于氧化，因此这些制剂主要为高铁血红蛋白。
其他說明
Review: Oxygen carrier proteins
Sales restrictions may apply
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Paul W Buehler et al.
Biomaterials, 31(13), 3723-3735 (2010-02-13)
Hemoglobin-based oxygen carriers (HBOC) are currently being developed as red blood cell (RBC) substitutes for use in transfusion medicine. Despite significant commercial development, late stage clinical results of polymerized hemoglobin (PolyHb) solutions hamper development. We synthesized two types of PolyHbs
M. Brunori et al.
Topics in Molecular and Structural Biology, 7, 263-263 (1985)
Kaori Yamazaki et al.
Clinical physiology and functional imaging, 33(2), 109-116 (2013-02-07)
Time-resolved spectroscopy (TRS-20) measures tissue oxygen saturation (%) by evaluating the absolute concentrations of oxygenated, deoxygenated and total haemoglobin based on measurement of the transit time of individual photons through a tissue of interest. We measured tissue oxygen saturation in
J L Schei et al.
Neuroscience, 227, 191-200 (2012-10-09)
Coupling between neural activity and hemodynamic responses is important in understanding brain function, interpreting brain-imaging signals, and assessing pathological conditions. Tissue state is a major factor in neurovascular coupling and may alter the relationship between neural and hemodynamic activity. However
Dafna Ben Bashat et al.
PloS one, 7(11), e49416-e49416 (2012-12-05)
Blood oxygenation level dependence (BOLD) imaging under either hypercapnia or hyperoxia has been used to study neuronal activation and for assessment of various brain pathologies. We evaluated the benefit of a combined protocol of BOLD imaging during both hyperoxic and
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