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重要文件

41639

Sigma-Aldrich

二甲基亚砜

BioUltra, for molecular biology, ≥99.5% (GC)

同義詞:

DMSO, 甲基亚砜

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About This Item

線性公式:
(CH3)2SO
CAS號碼:
分子量::
78.13
Beilstein:
506008
EC號碼:
MDL號碼:
分類程式碼代碼:
12191502
PubChem物質ID:
NACRES:
NA.25
等級:
for molecular biology
化驗:
≥99.5% (GC)
bp:
189 °C (lit.)
蒸汽壓力:
0.42 mmHg ( 20 °C)
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等級

for molecular biology

品質等級

蒸汽密度

2.7 (vs air)

蒸汽壓力

0.42 mmHg ( 20 °C)

產品線

BioUltra

化驗

≥99.5% (GC)

形狀

liquid

自燃溫度

573 °F

expl. lim.

42 %, 63 °F

雜質

Dnases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected
≤0.001% free acid (as CH3COOH)

蒸發殘留物

≤0.005%

顏色

colorless

折射率

n20/D 1.479 (lit.)
n20/D 1.479

bp

189 °C (lit.)

mp

16-19 °C (lit.)

溶解度

H2O: miscible (completely)

密度

1.10 g/mL (lit.)

正離子痕跡

Al: ≤0.5 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.02 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.5 mg/kg
K: ≤0.5 mg/kg
Li: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.1 mg/kg
Na: ≤1 mg/kg
Ni: ≤0.5 mg/kg
Pb: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

SMILES 字串

CS(C)=O

&lambda ;

neat

紫外吸收

λ: 280 nm Amax: 0.22

適合性

suitable for molecular biology

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI 密鑰

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

二甲基亚砜(DMSO)是一种有效的非质子溶剂,无色、无味,且天然具有吸湿性。DMSO可增强各种亲水和亲脂性通透剂的通透性。[1]它是广泛使用的实验室溶剂之一。[2]

應用

二甲基亚砜(DMSO)用作各种实验研究的化合物检测工具。[3][4]在淀粉样蛋白ββ聚集实验方案中,它可作为溶剂重新溶解多肽以维持其解离状态。[5]

注意

在室温下容易过冷并缓慢重融。 固化产品可以通过加热至室温来重新液化,而不会损害产品。

其他說明

Polybrene/DMSO 辅助的基因转移[6]

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

188.6 °F - closed cup

閃點(°C)

87 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons
Ungureanu A, et al.
Scientific reports, 6, 25841-25841 (2016)
The use of dimethylsulfoxide as a vehicle in cell culture experiments using ovarian carcinoma cell lines
Rodriguez-Burford C, et al.
Biotechniques, 78(1), 17-21 (2003)
R Aubin et al.
Methods in molecular biology (Clifton, N.J.), 7, 35-43 (1991-01-01)
Efforts to expand the current repertory of cell types amenable to transfection have often been thwarted by a common obstacle-namely, the low tolerance displayed by the recipient cells toward the gene-transfer regimen itself. As a result, several laboratories have turned
Developmental toxicity assay using high content screening of zebrafish embryos
Lantz-McPeak S, et al.
Journal of Applied Toxicology, 35(3), 261-272 (2015)
Topical and Transdermal Drug Delivery
Handbook of non-invasive drug delivery systems: science and technology (2009)

Questions

1–9 of 9 Questions  
  1. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  2. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    1 answer
    1. DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

      Helpful?

  3. What is Sure/Seal™ packaging?

    1 answer
    1. The Aldrich Sure/Seal™ packaging system is useful in the handling and storage of air-sensitive reagents.

      Helpful?

  4. Does DMSO have any synthetic utility?

    1 answer
    1. DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.

      Helpful?

  5. Is Dimethyl sulfoxide a sterile product?

    1 answer
    1. No, this product is not considered sterile.  Product Nos. D2560 and D2438 are sterile-filtered.

      Helpful?

  6. What is the DMSO dissolved in?

    1 answer
    1. DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

      Helpful?

  7. What is the molarity of DMSO?

    1 answer
    1. DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

      Helpful?

  8. What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?

    1 answer
    1. DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.

      Helpful?

  9. Where does DMSO come from?

    1 answer
    1. DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

      Helpful?

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