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259R-1

Sigma-Aldrich

Glucagon (EP74) Rabbit Monoclonal Primary Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP74, monoclonal

描述

(For In Vitro Diagnostic Use in Select Regions (See Chart))

形狀

buffered aqueous solution

物種活性

human

包裝

bottle of 1.0 mL predilute (259R-17)
bottle of 7.0 mL predilute (259R-18)
vial of 0.1 mL concentrate (259R-14)
vial of 0.5 mL concentrate (259R-15)
vial of 1.0 mL concentrate (259R-16)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200

同型

IgG

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

human ... GCG(2641)

一般說明

The normal islets of Langerhans (pancreas) contain four major cell types, 15-20% of which are alpha cells which produce glucagon.1 Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome2 (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.3 Immunohistochemically, the two types of glucagonomas are reactive to the glucagon antibody, though occasionally only weakly.

品質


IVD

IVD

IVD

RUO

聯結

Glucagon Positive Control Slides, Product No. 259S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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George J Netto et al.
Pathology, 42(4), 384-394 (2010-05-05)
Compared to other solid tumours such as breast, colon, and lung, the current clinical management of urological malignancies is lagging behind in terms of utilisation of clinically robust molecular tests that can identify patients that are more likely to respond
Q A Hamid et al.
Histopathology, 10(2), 119-133 (1986-02-01)
Histological diagnosis of neuroendocrine tumours can be hampered by their lack of peptide or amine immunoreactivity. In order to assess the usefulness of a range of specific and general markers of neuroendocrine differentiation, 10 pancreatic endocrine tumours, associated with high

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