推薦產品
生物源
rabbit
品質等級
100
500
共軛
unconjugated
抗體表格
Ig fraction of antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (259A-14)
vial of 0.5 mL concentrate (259A-15)
bottle of 1.0 mL predilute (259A-17)
vial of 1.0 mL concentrate (259A-16)
bottle of 7.0 mL predilute (259A-18)
製造商／商標名
Cell Marque®
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
控制
pancreas
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic
基因資訊
human ... GCG(2641)
一般說明
The normal islets of Langerhans (pancreas) contain four major cell types, 15-20% of which are alpha cells which produce glucagon.[1] Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome[2] (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.[3]Immunohistochemically, the two types of glucagonoma are reactive to the glucagon antibody, though occasionally only weakly.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
Glucagon (polyclonal) Positive Control Slides, Product No. 259S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: [email protected]
法律資訊
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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分析證明 (COA)
Lot/Batch Number
Aixia Sun et al.
Transplantation direct, 10(7), e1658-e1658 (2024-06-17)
Transplantation of human-induced pluripotent stem cell (hiPSC)-derived islet organoids is a promising cell replacement therapy for type 1 diabetes (T1D). It is important to improve the efficacy of islet organoids transplantation by identifying new transplantation sites with high vascularization and
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications (2010)
Rosai and Ackerman's Surgical Pathology, 10th ed., 1030-1031 (2011)
Yang Xiao et al.
Diabetologia, 66(6), 1142-1155 (2023-03-15)
Glucagon-stimulated hepatic gluconeogenesis contributes to endogenous glucose production during fasting. Recent studies suggest that TGF-β is able to promote hepatic gluconeogenesis in mice. However, the physiological relevance of serum TGF-β levels to human glucose metabolism and the mechanism by which
Q A Hamid et al.
Histopathology, 10(2), 119-133 (1986-02-01)
Histological diagnosis of neuroendocrine tumours can be hampered by their lack of peptide or amine immunoreactivity. In order to assess the usefulness of a range of specific and general markers of neuroendocrine differentiation, 10 pancreatic endocrine tumours, associated with high
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