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重要文件

Y0000530

Sultamicillin

European Pharmacopoeia (EP) Reference Standard

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About This Item

經驗公式(希爾表示法):
C25H30N4O9S2
CAS號碼:
分子量::
594.66
分類程式碼代碼:
41116107
NACRES:
NA.24
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等級

pharmaceutical primary standard

API 家族

sultamicillin

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

[S]1(=O)(=O)C2N([C@H](C1(C)C)C(=O)OCOC(=O)[C@@H]3N4C(SC3(C)C)C(C4=O)NC(=O)[C@@H](N)c5ccccc5)C(=O)C2

InChI

1S/C25H30N4O9S2/c1-24(2)17(29-20(32)16(21(29)39-24)27-19(31)15(26)12-8-6-5-7-9-12)22(33)37-11-38-23(34)18-25(3,4)40(35,36)14-10-13(30)28(14)18/h5-9,14-18,21H,10-11,26H2,1-4H3,(H,27,31)/t14?,15-,16?,17-,18-,21?/m0/s1

InChI 密鑰

OPYGFNJSCUDTBT-CUUJHUNTSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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分析證明 (COA)

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Ralf Smeets et al.
The International journal of oral & maxillofacial implants, 32(6), 1338–1345-1338–1345 (2017-10-14)
To test the antimicrobial properties, surface topography, reaction of surrounding tissue (biocompatibility), and osseointegration of ultrathin implant surfaces containing polysiloxane and nanoscaled silver particles. Implants with polysiloxane coating and nanoscaled silver particles (Ag/SiO Roughness parameters did not differ between all
Efficacy and safety of sultamicillin (750 mg bid) compared with amoxycillin/clavulanate (625 mg tid) in patients with umcomplicated urinary tract infections.
Schutz W.
International Journal of Antimicrobial Agents, 6, S55-S59 (1996)
H A Friedel et al.
Drugs, 37(4), 491-522 (1989-04-01)
Sultamicillin is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would
HPLC for in-process control in the production of sultamicillin.
Laviana L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 31(2), 321-328 (2003)
Efficacy and safety of Sultamicillin (Ampicillin/Sulbactan) and Amoxicillin/Clavulanic Acid in the treatment of upper respiratory tract infections in adults: an open-label, multicentric, randomized trial.
Ferreira J B, et al.
Revista Brasileira de Otorrinolaringologia, 72(1), 104-111 (2006)

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