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重要文件

Y0000462

托拉塞米

European Pharmacopoeia (EP) Reference Standard

同義詞:

Torsemide, Demadex, N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide

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About This Item

經驗公式(希爾表示法):
C16H20N4O3S
CAS號碼:
分子量::
348.42
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
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等級

pharmaceutical primary standard

API 家族

torasemide

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

形式

neat

SMILES 字串

CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc2cccc(C)c2

InChI

1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)

InChI 密鑰

NGBFQHCMQULJNZ-UHFFFAOYSA-N

基因資訊

human ... SLC12A1(6557)

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Torasemide for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

Torsemide is a loop diuretic and inhibitor of the Na+/K+/2Cl- carrier system.
Torsemide is a loop diuretic of the pyridine-sulfonylurea class with antialdosteronergic properties and inhibitor of the Na+/K+/2Cl- carrier system.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

[Treatment of nephritic edema by torasemide in children].
Qi Li et al.
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 13(6), 520-521 (2011-06-16)
Clinical therapeutics, 33(9), 1204-1213 (2011-09-13)
The pharmacologic modification of the synthesis and deposition of fibrillar collagen in the myocardium may have effects on the cardiac function, clinical status, and prognosis of patients with heart failure (HF). Serum procollagen type I carboxyterminal peptide (PICP) is a
Cuixia Li et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 1084-1090 (2011-06-11)
In pH 0.6-1.1 HCl-NaAc buffer solution, torasemide (TOR) reacted with TP to form a 3:1 ion-association complexes. As a result, not only the absorption spectra were changed, but also the intensities of resonance Rayleigh scattering (RRS), second-order scattering (SOS) and
[Etiologies of nephrotic syndrome].
S Heeringa et al.
Praxis, 100(9), 505-514 (2011-04-29)
Agents with antialdosterone properties should be the preferred diuretics for reducing hypertension related atrial fibrillation.
Oscar M P Jolobe
European journal of internal medicine, 21(1), 55-55 (2010-02-04)

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