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重要文件

PHR1684

Supelco

卡比马唑

Pharmaceutical Secondary Standard; Certified Reference Material

同義詞:

卡比马唑

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About This Item

經驗公式(希爾表示法):
C7H10N2O2S
CAS號碼:
分子量::
186.23
EC號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24
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等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. C0465000

API 家族

carbimazole

CofA

current certificate can be downloaded

包裝

pkg of 1 g

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

S=[c]1[n](cc[n]1C(=O)OCC)C

InChI

1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3

InChI 密鑰

CFOYWRHIYXMDOT-UHFFFAOYSA-N

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一般說明

Carbimazole is an orally administered thioimidazole drug, which is indicated for the management of hyperthyroidism as well as Grave′s disease in humans. It is used to facilitate the growth of animals for human consumption.[1]
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Carbimazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.[2][3][4]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA6300 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Determination of methimazole and carbimazole by flow-injection with chemiluminescence detection based on the inhibition of the Cu (II)-catalysed luminol-hydrogen peroxide reaction
Economou A, et al.
Analytica Chimica Acta, 505(1), 129-133 (2004)
Chromatographic methods development, validation and degradation characterization of the antithyroid drug Carbimazole
Abdelrahman MM
Biomedical Chromatography, 33(4), e4472-e4472 (2019)
Study of the British Pharmacopeia method on methimazole (thiamazole) content in carbimazole tablets
Aletrari M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 16(5), 785-792 (1998)
HPLC and GC?MS screening of Chinese proprietary medicine for undeclared therapeutic substances.
Liu SY, et al.
Journal of Pharmaceutical and Biomedical Analysis, 24(5-6), 983-992 (2001)

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