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重要文件

PHR1081

Supelco

水杨酸乙基己酯

Pharmaceutical Secondary Standard; Certified Reference Material

同義詞:

水杨酸-2-乙基己基酯, 柳酸辛酯, 水杨酸辛酯

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About This Item

線性公式:
(HO)C6H4CO2CH2CH(C2H5)(CH2)3CH3
CAS號碼:
分子量::
250.33
Beilstein:
2730664
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
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等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to USP 1477943

API 家族

octisalate

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.502 (lit.)

bp

189-190 °C/21 mmHg (lit.)

密度

1.014 g/mL at 25 °C (lit.)

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

SMILES 字串

CCCCC(CC)COC(=O)c1ccccc1O

InChI

1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3

InChI 密鑰

FMRHJJZUHUTGKE-UHFFFAOYSA-N

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一般說明

水杨酸辛酯(Octisalate )是一种防晒剂,可充当UVB(280-315 nm)辐射的UV过滤剂。[1]
用于质量控制的药物二级标准品CRM,为制药行业实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

應用

水杨酸辛酯可用作药物参考标准品,用于通过色谱法测定药物和防晒霜制剂中的分析物。[2][3]
这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析報告

这些二级标准品可追溯至USP、EP(PhEur)和BP一级标准品。

其他說明

本有证标准物质 (CRM) 按照 ISO 17034 ISO/IEC 17025 生产和认证。有关本 CRM 使用的所有信息,请参见检验报告。

腳註

想要查看本品的分析证书示例,请在下框中输入LRAC0298。这只是一个示例证书,可能与您收到的批次不符。

相關產品

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Chronic 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

323.6 °F - closed cup

閃點(°C)

162 °C - closed cup


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分析證明 (COA)

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存取文件庫

Thin layer chromatography-spray mass spectrometry: a method for easy identification of synthesis products and UV filters from TLC aluminum foils
Himmelsbach M, et al.
Analytical and Bioanalytical Chemistry, 406(15), 3647-3656 (2014)
Octisalate
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 43(3), 3194-3194 (2018)
Development and Validation of RP-HPLC Method for Analysis of Four UV Filters in Sunscreen Products
Yousef AN, et al.
International Journal of Pharmaceutical Sciences Review and Research (2013)
Beatriz Albero et al.
Journal of chromatography. A, 1248, 9-17 (2012-06-12)
The determination of organic contaminants in soil is a real challenge due to the large number of these compounds with quite different physico-chemical properties. In the present work, an analytical method was developed for the simultaneous determination in soil of
P Clarys et al.
Journal of dermatological science, 27(2), 77-81 (2001-09-05)
Temperature influences the stratum corneum adsorption of several topically applied compounds. This study was designed to evaluate the influence of the temperature on the stratum corneum adsorption of 3 UV filters. The UV filters were solubilized in two vehicles, an

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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