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Key Documents

P6555

Sigma-Aldrich

钾离子荧光探针(PBFI-AM)

≥90% (HPLC)

同義詞:

钾离子探针 PBFI-AM, 钾结合性苯并呋喃间苯二甲酸-AM

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About This Item

經驗公式(希爾表示法):
C58H62N2O24
CAS號碼:
分子量::
1171.11
MDL號碼:
分類程式碼代碼:
12171500

化驗

≥90% (HPLC)

儲存溫度

−20°C

SMILES 字串

COc1cc2cc(oc2cc1N3CCOCCOCCN(CCOCCOCC3)c4cc5oc(cc5cc4OC)-c6ccc(cc6C(=O)OCOC(C)=O)C(=O)OCOC(C)=O)-c7ccc(cc7C(=O)OCOC(C)=O)C(=O)OCOC(C)=O

InChI

1S/C58H62N2O24/c1-35(61)75-31-79-55(65)39-7-9-43(45(23-39)57(67)81-33-77-37(3)63)51-25-41-27-53(69-5)47(29-49(41)83-51)59-11-15-71-19-21-73-17-13-60(14-18-74-22-20-72-16-12-59)48-30-50-42(28-54(48)70-6)26-52(84-50)44-10-8-40(56(66)80-32-76-36(2)62)24-46(44)58(68)82-34-78-38(4)64/h7-10,23-30H,11-22,31-34H2,1-6H3

InChI 密鑰

AUKRBWNSOWVABU-UHFFFAOYSA-N

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應用

Cell permeable fluorescent probe for potassium.

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分析證明 (COA)

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P Jezek et al.
The Journal of biological chemistry, 265(18), 10522-10526 (1990-06-25)
New indicators for fluorescent measurement of Na+ and K+ ions should prove particularly useful for studies of reconstituted carriers of these ions. We show that PBFI, a K(+)-specific probe, provides a convenient and sensitive assay for the study of K+
P Paucek et al.
The Journal of biological chemistry, 267(36), 26062-26069 (1992-12-25)
The transport properties of mitochondria are such that net potassium flux across the inner membrane determines mitochondrial volume. It has been known that K+ uptake is mediated by diffusive leak driven by the high electrical membrane potential maintained by redox-driven
X Chen et al.
Biochemistry, 33(46), 13769-13774 (1994-11-22)
Although the predominance of plasmalogens in electrically-active membranes (e.g., sarcolemma) is well-known, identification of the molecular mechanisms through which the vinyl ether linkage facilitates electrophysiologic function has remained elusive. Herein we demonstrate that the kinetics of both carrier-mediated (i.e., valinomycin)
K Venema et al.
Biochimica et biophysica acta, 1146(1), 87-96 (1993-02-23)
Liposomes of egg PC/PG (8:2, mol/mol) were multilabelled with PBFI, pyranine and oxonol VI, fluorescent probes for, respectively, K+, H+ and membrane potential. Monitoring fluorescence with a multichannel photoncounting spectrofluorometer during K+ filling experiments allowed to measure K+ influx, the

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