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文件

F0290000

Flutrimazole

European Pharmacopoeia (EP) Reference Standard

同義詞:

1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole

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About This Item

經驗公式(希爾表示法):
C22H16F2N2
CAS號碼:
分子量::
346.37
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

flutrimazole

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

InChI

1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H

InChI 密鑰

QHMWCHQXCUNUAK-UHFFFAOYSA-N

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Flutrimazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

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J García Rafanell et al.
Arzneimittel-Forschung, 42(6), 836-840 (1992-06-01)
1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole (flutrimazole, UR-4056, CAS 119006-77-8) is a new topical imidazole antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans (MIC = 0.025-5.0 micrograms/ml). In most of these
del Palacio et al.
Mycoses, 38(9-10), 395-403 (1995-09-01)
In a double-blind, randomized study the efficacy and tolerance of flutrimazole 1% solution were compared with bifonazole 1% solution, applied once daily for 4 weeks, in 40 patients with culturally proven dermatophytosis or cutaneous candidosis. Forty patients with mycologically proven
A Alomar et al.
Dermatology (Basel, Switzerland), 190(4), 295-300 (1995-01-01)
Flutrimazole is a new imidazole derivate. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole. To compare the efficacy and tolerability of flutrimazole cream 1%
Synthesis and antifungal activity of a series of difluorotritylimidazoles.
J Bartrolí et al.
Arzneimittel-Forschung, 42(6), 832-835 (1992-06-01)
[Facial dermatophytide reaction].
B Monteagudo Sánchez et al.
Anales de pediatria (Barcelona, Spain : 2003), 68(4), 411-412 (2008-04-09)

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